ZR751_BREAST


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Circle Hunter Prediction

ID Value
ATCC CRL-1500
DSMZ None
Cellosaurus ZR-75-1
Cosmic None

Property Value
% Polyploidy 1.2
Ploidy Classification hypertriploid
Modal Chromosome Number 72.0
Modal Range Numeric 71-80
Marker Chromosomes Average Field 18.0
Primary or Metastasis Metastasis
Count of SV's 10

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: This human cell line has a hypertriploid chromosome number. The modal chromosome number was 72 occurring in 26% of the cells and the rate of higher ploidies was at 1.2%. Eighteen markers were common.They are: t(1q,?), M2,M3, del(3) (p21), der(5)t(5;?) (q35;?), del(6) (q21), t(11q14q), t(11;11) (p15;q11), der(14)t(2;14) (q21;q32), t(17q,?), M13, M14, M15, M16, M17, der(8)t(8;?), t(9p,?) and 19pt. Of these M13 was paired. Normal N14 was not found. N6 was single copied, X had 3 copies and N18 had 4 copies in each cell.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

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Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA', 'Linear amplification']

Predicted Genes on ecDNA

['ADGRA2', 'ADRB3', 'ANK1', 'AP3M2', 'ASH2L', 'BAG4', 'BRF2', 'C8orf86', 'CHRNB3', 'DDHD2', 'DKK4', 'EIF4EBP1', 'ERLIN2', 'FGFR1', 'GINS4', 'GOLGA7', 'GOT1L1', 'GPAT4', 'IKBKB', 'KAT6A', 'LETM2', 'LSM1', 'NKX6-3', 'NSD3', 'PLAT', 'PLPBP', 'PLPP5', 'POLB', 'RAB11FIP1', 'SFRP1', 'SLC20A2', 'SMIM19', 'SNORD65B', 'STAR', 'VDAC3', 'ZMAT4', 'ZNF703']

Predicted Features

Class Amplicon Complexity Score
ecDNA 1 0.6021796267
Image 1

Class Amplicon Complexity Score
Linear amplification 2 0.6813188302
Image 2

Class Amplicon Complexity Score
Linear amplification 3 0.6331447418
Image 3

Class Amplicon Complexity Score
Linear amplification 4 0.6238116241
Image 4

Class Amplicon Complexity Score
Linear amplification 5 0.5935497244
Image 5

Prediction

ecDNA: negative


Prediction

No data