U2OS_BONE


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Circle Hunter Prediction

ID Value
ATCC HTB-96
DSMZ ACC-785
Cellosaurus U2OS
Cosmic 909776.0

Property Value
% Polyploidy None
Ploidy Classification hypertriploid
Modal Chromosome Number None
Modal Range Numeric 71-80
Marker Chromosomes Average Field None
Primary or Metastasis Primary
Count of SV's 5

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: Cell line U-2 OS is chromosomally highly altered, with chromosome counts in the hypertriploid range. We did not find the hypodiploid cell population described by J. Ponten, et al., Instead, most of the population has slightly higher counts than first described. Very few normal chromosomes are present, but a high number of stable marker chromosomes are identified., Different chromosomal rearrangements involving the same chromosomes (N1, N7, N9, and N11 particularly), are seen. Twenty-two markers are found including: t(9qter--->9q21::1p36--->1p::?), 7p+, iso(17q), t(15q;?), 4q+, del(3)(q21), 5q(aberrant) and others.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

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Prediction

ecDNA Amplicon Predicted: N

Predicted Amplicon Classes: ['Complex non-cyclic', 'Linear amplification']

Predicted Genes on ecDNA

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Predicted Features

Class Amplicon Complexity Score
Complex non-cyclic 2 0.9020594628
Image 1

Class Amplicon Complexity Score
Linear amplification 3 0.212156173
Image 2

Prediction

ecDNA: positive

Genes: .


Prediction

No data