Available Data

Vendor Karyotype
Amplicon Architect Prediction
Circle Hunter Prediction
Shatterseek Prediction

ID	Value
ATCC	TIB-202
DSMZ	ACC-16
Cellosaurus	THP-1
Cosmic	909771.0

Karyotype Details

Property	Value
% Polyploidy	None
Ploidy Classification	hypertetraploid
Modal Chromosome Number	94.0
Modal Range Numeric	88-96
Marker Chromosomes Average Field	2.0
Primary or Metastasis	Primary
Count of SV's	10

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human near-tetraploid karyotype - 94(88-96)<4n>XY/XXY, -Y, +1, +3, +6, +6, -8, -13, -19, -22, -22, +2mar, add(1)(p11), del(1)(q42.2), i(2q), del(6)(p21)x2-4, i(7p), der(9)t(9;11)(p22;q23)i(9)(p10)x2, der(11)t(9;11)(p22;q23)x2, add(12)(q24)x1-2, der(13)t(8;13)(p11;p12), add(?18)(q21) - carries t(9;11) associated with AML M5

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA']

Predicted Genes on ecDNA

['BMP8A', 'BMP8B', 'CAP1', 'CITED4', 'COL9A2', 'EXO5', 'HEYL', 'HPCAL4', 'KCNQ4', 'MFSD2A', 'MYCL', 'NFYC', 'NFYC-AS1', 'NT5C1A', 'OXCT2', 'OXCT2P1', 'PABPC4', 'PABPC4-AS1', 'PPIE', 'PPIEL', 'PPT1', 'RIMS3', 'RLF', 'SMAP2', 'SNORA55', 'TMCO2', 'TRIT1', 'ZFP69', 'ZFP69B', 'ZMPSTE24', 'ZNF684', 'KDM4A', 'KDM4A-AS1', 'PTPRF', 'ST3GAL3']

Predicted Features

View Feature 1 - THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE ecDNA

Class	Amplicon	Complexity Score
ecDNA	1	0.6357044942

View Feature 2 - THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE ecDNA

Class	Amplicon	Complexity Score
ecDNA	1	1.272028498

Prediction

ecDNA: positive

Genes: .;RPS2P12,OAZ1P1,RNU6-1237P,RPL21P2,LOC1328982,GTF2F2P2

Prediction

Shatterseek Prediction: No Chromothripsis Detected

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: None