T47D_BREAST


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction
  • Circle Hunter Prediction
  • Shatterseek Prediction

ID Value
ATCC HTB-133
DSMZ ACC-739
Cellosaurus T-47D
Cosmic 905945.0

Property Value
% Polyploidy 0.8
Ploidy Classification hypotriploid
Modal Chromosome Number 65.0
Modal Range Numeric 58-68
Marker Chromosomes Average Field 18.0
Primary or Metastasis Metastasis
Count of SV's 5

Details

ecDNA Present (Y/N/P): Y

Literature source: https://onlinelibrary.wiley.com/doi/full/10.1002/1098-2264%28200007%2928%3A3%3C308%3A%3AAID-GCC9%3E3.0.CO%3B2-B

HSR Classification: N

ATCC Karyotype: This is a hypotriploid human cell line. The modal chromosome number is 65 occurring at 50% and polyploidy at 0.8%. 18 marker chromosomes are common to most cells, of which 7 are paired and 11 are single-copied. The t(8q14q), t(9q17q), t(10q17p) are among 7 paired markers common to most cells. N7, N9, and N10 are absent and N11 is generally present in 4 copies. DM's occurred, but infrequently. Q-band examination did not show the presence of a Y chromosome.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: DM's occurred, but infrequently.

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Prediction

ecDNA Amplicon Predicted: N

Predicted Amplicon Classes: []

Predicted Genes on ecDNA

[]

Predicted Features

No features detected.


Prediction

ecDNA: positive

Genes: BRD9P2


Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 1, 5