SW480_LARGE_INTESTINE
Available Data
- Vendor Karyotype
- ecDNA Presence Verification from Literature
- Amplicon Architect Prediction
- Circle Hunter Prediction
- Shatterseek Prediction
| Property | Value |
|---|---|
| % Polyploidy | 12.0 |
| Ploidy Classification | mix(hypotriploid, hyperdiploid) |
| Modal Chromosome Number | 58.0 |
| Modal Range Numeric | 51-58 |
| Marker Chromosomes Average Field | None |
| Primary or Metastasis | Primary |
| Count of SV's | 12 |
Details
ecDNA Present (Y/N/P): Y
Literature source:
https://www.nature.com/articles/nature21356
HSR Classification: N
ATCC Karyotype: The stemline chromosome number is hypotriploid and 11-12 marker chromosomes were common. Both double minutes and dicentrics were observed in 8% of each metaphase examined.
DSMZ Karyotype: human hypotriploid karyotype with 12% polyploidy - 58(51-58)<3n>XX, -Y, -1, -3, -4, -5, -6, +7, -8, -10, -12, -15, -18, -19, +20, -22, der(1)t(1;9)(q22;q12), t(2;12)(q35;q13.1), del(5)(q13.2q32), add(7)(q35), dup(7)(q11.22q21.3), der(8)t(1;8)(p11;p11)t(1;9)(q22;q12), add(10)(p14), inv(14)(q13q32), del(18)(q12.2), der(19)t(6;19)(p11;q13), der(20)t(14;20)(q13;p13)x2 - identified by large submetacentric der(2)t(2;12) marker
Heterogeneity Indications and Other Notes: No data
Prediction
ecDNA Amplicon Predicted: Y
Predicted Amplicon Classes: ['ecDNA', 'Complex non-cyclic', 'Linear amplification']
Predicted Genes on ecDNA
Predicted Features
View Feature 1 - SW480_LARGE_INTESTINE ecDNA
| Class | Amplicon | Complexity Score |
|---|---|---|
| ecDNA | 1 | 2.392990202 |
View Feature 2 - SW480_LARGE_INTESTINE Complex non-cyclic
| Class | Amplicon | Complexity Score |
|---|---|---|
| Complex non-cyclic | 2 | 0.9188546246 |
View Feature 3 - SW480_LARGE_INTESTINE Complex non-cyclic
| Class | Amplicon | Complexity Score |
|---|---|---|
| Complex non-cyclic | 3 | 2.155535931 |
View Feature 4 - SW480_LARGE_INTESTINE Linear amplification
| Class | Amplicon | Complexity Score |
|---|---|---|
| Linear amplification | 4 | 0.0 |
View Feature 5 - SW480_LARGE_INTESTINE Linear amplification
| Class | Amplicon | Complexity Score |
|---|---|---|
| Linear amplification | 5 | 0.0 |
Prediction
ecDNA: positive
Genes: .
Prediction
Shatterseek Prediction: High Confidence
Shatterseek High Confidence Chromosomes: 2
Shatterseek Low Confidence Chromosomes: 6, 9, 13