SW1783_CENTRAL_NERVOUS_SYSTEM


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Shatterseek Prediction

ID Value
ATCC HTB-13
DSMZ None
Cellosaurus SW1783
Cosmic 909750.0

Property Value
% Polyploidy 10.1
Ploidy Classification hypertetraploid
Modal Chromosome Number 96.0
Modal Range Numeric 93-103
Marker Chromosomes Average Field 10.0
Primary or Metastasis Primary
Count of SV's 6

Details

ecDNA Present (Y/N/P): Y

HSR Classification: N

ATCC Karyotype: hypertetraploid; modal number = 96. The rate of higher ploidies was 10.1%. The markers der(5)t(1;5) (p11;p15), t(1q3q), del(3) (q21), der(6)t(6;11) (p12;p15), der(11)t(6;11) (p12;p15), and 5 others were common to most cells. Of these, der (6) and der(11) had consistently two copies per cell, and were probably formed by balanced translocation between N6 and N11. Nine to 10 marker chromosomes were common to some cells, and 10 to 15 others were detected only once. All normal chromosomes were present in 2 to 5 copies per cell. Generally X had 3 copies and Y had 2 copies per cell. Double minutes (DM) were seen in some cells, and only 1 to a few copies occurred per cell.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA']

Predicted Genes on ecDNA

['AASDH', 'ARL9', 'CEP135', 'CHIC2', 'CLOCK', 'CRACD', 'EXOC1', 'EXOC1L', 'GSX2', 'HOPX', 'IGFBP7', 'IGFBP7-AS1', 'KDR', 'KIT', 'NMU', 'NOA1', 'PAICS', 'PDCL2', 'PDGFRA', 'POLR2B', 'PPAT', 'REST', 'RPL21P44', 'SPINK2', 'SRD5A3', 'SRD5A3-AS1', 'SRP72', 'THEGL', 'TMEM165']

Predicted Features

Class Amplicon Complexity Score
ecDNA 1 0.8318273262
Image 1

Prediction

ecDNA: None


Prediction

Shatterseek Prediction: High Confidence

Shatterseek High Confidence Chromosomes: 6

Shatterseek Low Confidence Chromosomes: None