Property | Value |
---|---|
% Polyploidy | 44.0 |
Ploidy Classification | mix (hypotriploid, hyperdiploid) |
Modal Chromosome Number | None |
Modal Range Numeric | 54-60 |
Marker Chromosomes Average Field | 20.0 |
Primary or Metastasis | Metastasis |
Count of SV's | 18 |
ecDNA Present (Y/N/P): N
HSR Classification: N
ATCC Karyotype: The stemline chromosome number is hypotriploid, with the 2S component occurring at 3.2%. Seventeen to 20 marker chromosomes were common to most S metaphases. Normal X, 13, and 19 chromosomes were absent, and chromosomes 2, 3, 14, 17 and 20 were generally monosomic. The Y chromosome was not detected using QM staining.
DSMZ Karyotype: human flat-moded hyperdiploid karyotype with 44% polyploidy - 54-60<2n>X, -Y, +1, +1, -2, +4, +5, +7, +7, +11, +13, +19, +22, +5mar, add(X)(p21), i(1q), del(1)(q12)x1-2, add(2)(q37), del(3)(p22p26), add(4)(q32), der(5)t(5;6)(p15;p11), del(5)(q13), add(7)(q11;abr), add(11)(q2)x2, add(13)(p12)x1-2, add(13)(p12), add(15)(p12), der(16)t(8;16)(q12;q23), del(17)(p11), add(19)(p13)x2-3 - sideline with additional der(7;8)(q10;p10), add(22)(q13), der(11)dup(11)(q13q22) - carries 3p-, 5q-, +7, 17p- associated with NSCLC - matches published karyotype
Heterogeneity Indications and Other Notes: No data
ecDNA Amplicon Predicted: Y
Predicted Amplicon Classes: ['Linear amplification', 'ecDNA', 'Complex non-cyclic']
View Feature 1 - SKMES1_LUNG Linear amplification
Class | Amplicon | Complexity Score |
---|---|---|
Linear amplification | 1 | 0.6929152139 |
View Feature 2 - SKMES1_LUNG ecDNA
Class | Amplicon | Complexity Score |
---|---|---|
ecDNA | 3 | 0.5398683613 |
View Feature 3 - SKMES1_LUNG Complex non-cyclic
Class | Amplicon | Complexity Score |
---|---|---|
Complex non-cyclic | 5 | 0.956816222 |
ecDNA: None
Shatterseek Prediction: High Confidence
Shatterseek High Confidence Chromosomes: 2, 4
Shatterseek Low Confidence Chromosomes: 5, 6