SKHEP1_LIVER


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Shatterseek Prediction

ID Value
ATCC HTB-52
DSMZ ACC-141
Cellosaurus SK-HEP-1
Cosmic 909719.0

Property Value
% Polyploidy 9.0
Ploidy Classification hypotriploid
Modal Chromosome Number 62.0
Modal Range Numeric 60-63
Marker Chromosomes Average Field 8.0
Primary or Metastasis Metastasis
Count of SV's 11

Details

ecDNA Present (Y/N/P): N

HSR Classification: Y

ATCC Karyotype: The cell line is aneuploid human (XX), with chromosome counts in the hypotriploid range. Normal chromosomes N1, N13, N14, N15, and N16 are clearly under-represented with respect to the copy number of other normal chromosomes, while chromosome N7, N12, and N17 tend to be over-represented in some metaphases. Eight markers are identified: del(1)(q21), der(1)t(1;2)(p36;q21), ?tdic(1;12)(p36;q24), ampl.t(4pter--->4q11::HSR::4q12--->4q24::HSR?::4q26--->4q35::2q15--->2pter), 13p+, 13p++, 14p+, t(14q15q), iso(14q), 19q+, del(3)(p14p24), 15p+.

DSMZ Karyotype: human hypotriploid karyotype with 9% polyploidy - 62(60-63)<3n>X, -X, -X, -4, +6, +7, -9, +12, -13, -14, -15, -16, -18, der(1;7)(p10;q10), ?der(2;20)(p10;q10), der(6;13)(p10;q10)x2-3, add(12)(p1?), i(14q), add(19)(p13), add(21)(p11) - sideline with add(15)(p11) - resembles published karyotype

Heterogeneity Indications and Other Notes: resembles published karyotype

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Prediction

ecDNA Amplicon Predicted: N

Predicted Amplicon Classes: []

Predicted Genes on ecDNA

[]

Predicted Features

No features detected.


Prediction

ecDNA: None


Prediction

Shatterseek Prediction: High Confidence

Shatterseek High Confidence Chromosomes: 9

Shatterseek Low Confidence Chromosomes: 6, 16