SCLC21H_LUNG


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction
  • Shatterseek Prediction

ID Value
ATCC None
DSMZ ACC-372
Cellosaurus None
Cosmic None

Property Value
% Polyploidy 12.0
Ploidy Classification hypodiploid
Modal Chromosome Number 42.0
Modal Range Numeric 40-42
Marker Chromosomes Average Field 2.0
Primary or Metastasis Metastasis
Count of SV's 10

Details

ecDNA Present (Y/N/P): Y

Literature source: https://aacrjournals.org/cancerdiscovery/article/13/4/928/725029/Extrachromosomal-DNA-Amplification-Contributes-to

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human hypodiploid karyotype with 12% polyploidy - 42(40-42)<2n>XY, +1, -2, -5, +6, -10, +11, -17, -18, -19, -21, +2mar, del(1)(p22p32), add(5)(p15), del(6)(q14), add(8)(p21), add(11)(q24), del(11)(p11), t(12;17)(q10;q10), del(13)(q12q14), add(15)(q25) - resembles published karyotype (and that of SCLC-16HC)

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA']

Predicted Genes on ecDNA

['CASC11', 'FAM167A-AS1', 'MYC', 'NIPAL2', 'POP1', 'LRRC38', 'TNFRSF18', 'TTLL10']

Predicted Features

Class Amplicon Complexity Score
ecDNA 1 0.6316214237
Image 1

Class Amplicon Complexity Score
ecDNA 1 1.276029069
Image 2

Prediction

ecDNA: None


Prediction

Shatterseek Prediction: High Confidence

Shatterseek High Confidence Chromosomes: 1, 3, 2008

Shatterseek Low Confidence Chromosomes: None