RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction
  • Circle Hunter Prediction

ID Value
ATCC CCL-155
DSMZ ACC-402
Cellosaurus RPMI-8226
Cosmic 905964.0

Property Value
% Polyploidy 7.5
Ploidy Classification mix (triploid, hypotriploid)
Modal Chromosome Number None
Modal Range Numeric 62-67
Marker Chromosomes Average Field 2.0
Primary or Metastasis Primary
Count of SV's 15

Details

ecDNA Present (Y/N/P): N

Literature source: https://www.nature.com/articles/nature21356

HSR Classification: N

ATCC Karyotype: Unstable karyotype in triploid range of 68-70 chromosomes. Two large marker chromosomes with terminal centromeres.

DSMZ Karyotype: human flat-moded hypotriploid karyotype with 7.5% polyploidy - 62-67<3n>XXY, -1, +5, +6, +7, -8, -9, -10, +11, -12, -13, -14, +16, +18, -19, +21, -22, der(1)t(1;1)(p36.3;q11-12), add(3)(q27-29)x2, del(4)(p14p15.4), der(5;6)(q10;p10)x1-2, del(5)(q32), del(6)(q15), add(9)(p24), add(11)(p15), del(11)(q25), der(14)t(1;14)(q11-12;q32)x2, del(15)(q11.2q14)x2, add(16)(q23-24), der(17)t(?8;17)(q21.2;q25), del(22)(q13.2) - der(1), 6q-, 14q+ and 22q- associated with multiple myeloma - identified by disomic 14q+

Heterogeneity Indications and Other Notes: No data

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Prediction

ecDNA Amplicon Predicted: N

Predicted Amplicon Classes: ['Linear amplification']

Predicted Genes on ecDNA

[]

Predicted Features

Class Amplicon Complexity Score
Linear amplification 1 0.6272728813
Image 1

Class Amplicon Complexity Score
Linear amplification 2 1.261845263
Image 2

Prediction

ecDNA: negative


Prediction

No data