RPMI7951_SKIN

Available Data

• Vendor Karyotype
• Amplicon Architect Prediction
• Shatterseek Prediction

IDs from Other Resources

Karyotype Details

Details

ecDNA Present (Y/N/P): N

HSR Classification: Y

ATCC Karyotype: modal number= 49; range = 47 to 66.This is a hyperdiploid human cell line with the modal chromosome number of 49, occurring in 24% of cells. Polyploid cells occurred at 22%, which is high. Seven marker chromosomes were common to most cells, including t(10p14q); t(15q17p), t(Xp8p), del(17) (p13.1) and three others. Five others occurred only in some cells. Normal X chromosomes were absent. N14, N17 and N22 were mostly single-copied and N2 had three copies. Fluorescence examination did not show the presence of any Y-like chromosome.

DSMZ Karyotype: human flat-moded hyperdiploid karyotype with 22% polyploidy - 54(50-60)<2n>X, -X, +1, +2, +6, +7, +8, +20, +20, +3mar, der(8)t(7;8)(p11;p12), der(9)t(9;11)(p21;q11), add(18)(q23;HSR) - shares t(9;11) with IPC-298 defining a new recurrent translocation in malignant melanoma

Heterogeneity Indications and Other Notes: shares t(9;11) with IPC-298 defining a new recurrent translocation in malignant melanoma