REC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Circle Hunter Prediction
  • Shatterseek Prediction

ID Value
ATCC CRL-3004
DSMZ ACC-584
Cellosaurus REC-1
Cosmic None

Property Value
% Polyploidy 25.0
Ploidy Classification hypodiploid
Modal Chromosome Number 45.0
Modal Range Numeric 41-47
Marker Chromosomes Average Field None
Primary or Metastasis None
Count of SV's 12

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: This is a near-diploid cell line of male origin with a modal chromosome number of 45 and a polyploidy rate of 10%. The karyotype is highly rearranged with most of the cells containing the t(11;14)(q13;q32) common to mantle cell lymphoma. Also, there are approximately 5-6 derivative chromosomes in the karyology that have been described by others. Note: Cytogenetic information is based on initial seed stock at ATCC.

DSMZ Karyotype: human highly rearranged flat-moded near-diploid karyotype with 25% polyploidy - 41-47<2n>XY/XXY, -2, -8, +11, +12, -13, -22, add(5)(p15), i(7q), add(9)(p22), der(9)t(9;17)(q3?1;q11-12), add(10)(q24-q25), add(11)(q11), t(11;14)(q13;q32), add(12)(q22), der(12)t(8;12)(q11;p12), der(12)t(12;16)(p11;p11), der(16)t(16;17)(p11;?q25)t(2;16)(p1?2;q2?1), der(16)t(16;22)(p13;q11), add(17)(q25)x2 - carries t(11;14) effecting rearrangement of IGH with CCND1/BCL1 - near tetraploid sideline with additional rearrangements present - matches published description

Heterogeneity Indications and Other Notes: No data

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Prediction

ecDNA Amplicon Predicted: N

Predicted Amplicon Classes: ['BFB']

Predicted Genes on ecDNA

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Predicted Features

Class Amplicon Complexity Score
BFB 1 1.079155406
Image 1

Prediction

ecDNA: negative


Prediction

Shatterseek Prediction: No Chromothripsis Detected

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: None