PC3_PROSTATE

Available Data

• Vendor Karyotype
• ecDNA Presence Verification from Literature
• Amplicon Architect Prediction
• Circle Hunter Prediction
• Shatterseek Prediction

IDs from Other Resources

Karyotype Details

Details

ecDNA Present (Y/N/P): Y

Literature source: https://pubmed.ncbi.nlm.nih.gov/7176035/
https://www.nature.com/articles/nature21356

HSR Classification: Y

ATCC Karyotype: The line is near-triploid with a modal number of 62 chromosomes. There are nearly 20 marker chromosomes commonly found in each cell; and normal N2, N3, N4, N5, N12, and N15 are not found. No normal Y chromosomes could be detected by Q-band analysis.

DSMZ Karyotype: human highly-rearranged flat-moded hypotetraploid karyotype with 3% polyploidy - 80-90<4n>XX/XXX, -Y, -1, -1, -2, -2, +3, +3, -4, -5, +7, -8, -8, -10, -10, -10, -10, -12, -13, +14, -15, -15, -16, -16, -17, -18, -18, -22, +18-21mar, +1-2dm, del(1)(p34p35), add(1p?32), add(3)(p1?), add(3)(q13), add(3)(q21)x2, del(5)(p1?)x1-2, add(9)(p1?1), del(9)(p21)x1-2, add(12)(q24), add(13)(p11), del(17)(p11), add(19)(p13) - sideline with der(3)add(3)(p2?5)add(3q2?), del(4)(q2?4q2?8), add(7)(q11), add(8)(p1?), add(9)(q34) - extensive genomic amplification of c-MYC in hsr present in markers - distantly related to published karyotype

Heterogeneity Indications and Other Notes: 1-2dm; extensive genomic amplification of c-MYC in hsr present in markers