Available Data

ecDNA Presence Verification from Literature
Amplicon Architect Prediction
Shatterseek Prediction

ID	Value
ATCC	CRL-5817
DSMZ	None
Cellosaurus	NCI-H889
Cosmic	None

Details

ecDNA Present (Y/N/P): Y

Literature source: https://aacrjournals.org/cancerdiscovery/article/13/4/928/725029/Extrachromosomal-DNA-Amplification-Contributes-to

HSR Classification: No data

ATCC Karyotype: No data

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA', 'Complex non-cyclic', 'BFB']

Predicted Genes on ecDNA

['AKIRIN1', 'BMP8A', 'BMP8B', 'GJA9', 'GJA9-MYCBP', 'HEYL', 'HPCAL4', 'KIAA0754', 'MACF1', 'MYCBP', 'MYCL', 'NDUFS5', 'NT5C1A', 'OXCT2', 'OXCT2P1', 'PABPC4', 'PABPC4-AS1', 'PPIE', 'PPIEL', 'RHBDL2', 'RLF', 'RRAGC', 'SNORA55', 'TRIT1', 'CEP128', 'DIO2', 'DIO2-AS1']

Predicted Features

View Feature 1 - NCIH889_LUNG ecDNA

Class	Amplicon	Complexity Score
ecDNA	1	0.4455910108

View Feature 2 - NCIH889_LUNG Complex non-cyclic

Class	Amplicon	Complexity Score
Complex non-cyclic	2	0.7180543366

View Feature 3 - NCIH889_LUNG BFB

Class	Amplicon	Complexity Score
BFB	3	1.398025723

View Feature 4 - NCIH889_LUNG ecDNA

Class	Amplicon	Complexity Score
ecDNA	4	0.5496213548

Prediction

ecDNA: None

Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 18, X