Property | Value |
---|---|
% Polyploidy | 3.0 |
Ploidy Classification | hypotriploid |
Modal Chromosome Number | 58.0 |
Modal Range Numeric | 58-68 |
Marker Chromosomes Average Field | 3.0 |
Primary or Metastasis | Metastasis |
Count of SV's | 1 |
ecDNA Present (Y/N/P): Y
Literature source:
https://www.sciencedirect.com/science/article/pii/S0165460805001561#bib10
https://aacrjournals.org/cancerdiscovery/article/13/4/928/725029/Extrachromosomal-DNA-Amplification-Contributes-to
HSR Classification: Y
ATCC Karyotype: This is a near triploid human cell line. The modal chromosome number is 58, occurring at 44% with polyploidy at 3%. Marker chromosomes der(1)t(1;709p13;p11), t(13q;?HSR;15q) and der(190t(19;?)(q13.4;?) were common to most cells., There were two distinct subpopulations readily distinguished by karyotype. Besides uniform changes in the numbers of copies of some normal chromosomes, one population had der(3)t(3;20)(p11;p11?), t(3q19p), i(7q) and a minute chromosome of unknown origin., The other had t(1q17p), del(1)(q21), der(3)t(3;7)(p12;q11) plus two other markers. Each cell had two copies of a normal X chromosome. The Y chromosome was not detected in Q banded preparations.
DSMZ Karyotype: No data
Heterogeneity Indications and Other Notes: a minute chromosome of unknown origin There were two distinct subpopulations readily distinguished by karyotype.
ecDNA Amplicon Predicted: Y
Predicted Amplicon Classes: ['ecDNA']
View Feature 1 - NCIH82_LUNG ecDNA
Class | Amplicon | Complexity Score |
---|---|---|
ecDNA | 1 | 0.9682448035 |
View Feature 2 - NCIH82_LUNG ecDNA
Class | Amplicon | Complexity Score |
---|---|---|
ecDNA | 1 | 0.4822271272 |
ecDNA: negative
Shatterseek Prediction: High Confidence
Shatterseek High Confidence Chromosomes: 2, 3
Shatterseek Low Confidence Chromosomes: 4