NCIH661_LUNG


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Shatterseek Prediction

ID Value
ATCC HTB-183
DSMZ None
Cellosaurus NCI-H661
Cosmic 687829.0

Property Value
% Polyploidy None
Ploidy Classification hyperhexaploid
Modal Chromosome Number 142.0
Modal Range Numeric 130-153
Marker Chromosomes Average Field 70.0
Primary or Metastasis Metastasis
Count of SV's 4

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: hyperhexaploid; modal number = 142; range = 130 to 153. Each cell had over 70 marker chromosomes. Among the markers were t(1p10q), del(1)(q11/q12), 6q+, 2q+,der(20)t(12;20)(q11;q13). Some of these had 2 to copies per cell. Most cells also had 5 to 10 microchromosomes (metacentric like). Structurally normal N2,N4 and N9 were absent; two copies of the X and multiple copies of the Y were detected.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: N

Predicted Amplicon Classes: ['Complex non-cyclic', 'BFB', 'Linear amplification']

Predicted Genes on ecDNA

[]

Predicted Features

Class Amplicon Complexity Score
BFB 10 1.264603165
Image 1

Class Amplicon Complexity Score
Complex non-cyclic 1 1.037864354
Image 2

Class Amplicon Complexity Score
Linear amplification 2 0.5986161053
Image 3

Class Amplicon Complexity Score
Linear amplification 3 0.6443259424
Image 4

Class Amplicon Complexity Score
Linear amplification 4 1e-10
Image 5

Class Amplicon Complexity Score
Linear amplification 5 0.8841924361
Image 6

Class Amplicon Complexity Score
Linear amplification 6 0.5758492372
Image 7

Class Amplicon Complexity Score
Complex non-cyclic 7 1.569134003
Image 8

Class Amplicon Complexity Score
Linear amplification 8 0.8543696951
Image 9

Class Amplicon Complexity Score
Linear amplification 9 0.4249921547
Image 10

Prediction

ecDNA: None


Prediction

Shatterseek Prediction: High Confidence

Shatterseek High Confidence Chromosomes: 4

Shatterseek Low Confidence Chromosomes: 6, 7, 8, 12