NCIH596_LUNG


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Shatterseek Prediction

ID Value
ATCC HTB-178
DSMZ None
Cellosaurus NCI-H596
Cosmic 908459.0

Property Value
% Polyploidy 2.9
Ploidy Classification hypertriploid
Modal Chromosome Number 71.0
Modal Range Numeric 70-80
Marker Chromosomes Average Field 11.0
Primary or Metastasis Primary
Count of SV's 7

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: modal number = 71; range = 65 to 75.This is a near triploid human cell line. The modal chromosome number was 71 although cells with 70 chromosomes occurred frequently. The frequency of higher ploidies was 2.9%.; Over 11 marker chromosomes were common to all cells, and at least 6 others were found in some cells. Among the common markers were: del(1)(p22), i(3q), i(6p), i(7p), t(7p17q), 14q+ and five others.; Of these, del(1) and i(7p) were generally double [occasionally triple for del(1)]. Constantly, there were 2 to 3 minute chromosomes that were about 1/2 the size of a G group chromosome.; Structurally normal N17 had only a single copy per cell, whereas N15 had four copies and N20 and N21 had four or more copies. The X chromosome was paired, but the Y was not found by fluorescence microscopy.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: there were 2 to 3 minute chromosomes that were about 1/2 the size of a G group chromosome

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA']

Predicted Genes on ecDNA

['C6orf141', 'CENPQ', 'GLYATL3', 'MMUT']

Predicted Features

Class Amplicon Complexity Score
ecDNA 1 0.6929834945
Image 1

Prediction

ecDNA: None


Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 5