NCIH522_LUNG


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction

ID Value
ATCC CRL-5810
DSMZ None
Cellosaurus NCI-H522
Cosmic 905944.0

Property Value
% Polyploidy 3.0
Ploidy Classification hyperdiploid
Modal Chromosome Number 53.0
Modal Range Numeric 47-57
Marker Chromosomes Average Field 11.0
Primary or Metastasis Primary
Count of SV's 6

Details

ecDNA Present (Y/N/P): Y

Literature source: https://www.nature.com/articles/nature21356

HSR Classification: N

ATCC Karyotype: modal number = 53. This is a hypotriploid human cell line with the modal chromosome number occurring in 68% of cells counted. The polyploid cells occurred at 3.0%; eleven marker chromosomes were common to all cells, of which two were paired. The markers included: der(6)(q13), t(7p17q), del(10)(p11.23), paired der(7)t(7;?17)(p22;?q21.1) and der(16)t(16;?)(q24;?), and six others; normal Y, N13, N15, and N16 were absent; the X chromosomes were mostly paired.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Linear amplification', 'Complex non-cyclic', 'ecDNA']

Predicted Genes on ecDNA

['PDGFC']

Predicted Features

Class Amplicon Complexity Score
Linear amplification 1 0.6520199335
Image 1

Class Amplicon Complexity Score
Complex non-cyclic 2 1.748070782
Image 2

Class Amplicon Complexity Score
ecDNA 3 0.6139331651
Image 3

Class Amplicon Complexity Score
Linear amplification 4 0.9385845446
Image 4

Class Amplicon Complexity Score
Complex non-cyclic 5 1.260289644
Image 5

Prediction

ecDNA: None


Prediction

No data