Available Data

Vendor Karyotype
ecDNA Presence Verification from Literature
Amplicon Architect Prediction

ID	Value
ATCC	HTB-177
DSMZ	ACC-737
Cellosaurus	NCI-H460
Cosmic	905943.0

Karyotype Details

Property	Value
% Polyploidy	1.7
Ploidy Classification	mix(hypotriploid, hyperdiploid)
Modal Chromosome Number	57.0
Modal Range Numeric	53-65
Marker Chromosomes Average Field	7.0
Primary or Metastasis	Metastasis
Count of SV's	4

Details

ecDNA Present (Y/N/P): Y

Literature source: https://www.nature.com/articles/nature21356

HSR Classification: N

ATCC Karyotype: modal numbr = 57; range = 53 to 65.This is a hypotriploid human cell line. The modal chromosome number is 57 although cells with 58 chromosomes occurred with a comparable frequency. The frequency of higher ploidies was 1.7%. Seven marker chromosomes, der(9)t(1;9)(q21;p24), der(9)t(7;9)(p11;p22), t(10q14q), der(16)t(7;16)(q11.23;q22), a small ring (about 1/2 the size of a G chromosome) and two others, were common to all cells. Three other markers were found in some cells only. The markers, t(7;9) and t(7;16) were mostly paired. Normal N9 was absent, and N7 and N16 had only a single copy per cell. Two copies each of the X and the Y were present in all cells.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: a small ring (about 1/2 the size of a G chromosome)

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