Available Data

ecDNA Presence Verification from Literature
Amplicon Architect Prediction
Shatterseek Prediction

ID	Value
ATCC	CRL-5928
DSMZ	None
Cellosaurus	NCI-H2170
Cosmic	687815.0

Details

ecDNA Present (Y/N/P): Y

Literature source: https://www.biorxiv.org/content/10.1101/2023.12.18.572197v1

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['BFB', 'ecDNA']

Predicted Genes on ecDNA

['CASC11', 'CASC21', 'CASC3', 'CASC8', 'CCAT2', 'CDC6', 'ERBB2', 'GRB7', 'IKZF3', 'MIEN1', 'MYC', 'PCAT1', 'PGAP3', 'PNMT', 'POU5F1B', 'PVT1', 'RAPGEFL1', 'RARA', 'STARD3', 'TCAP', 'TMEM75', 'WIPF2', 'ZPBP2', 'BRMS1L', 'CLEC14A', 'FBXO33', 'FOXA1', 'GEMIN2', 'INSM2', 'MBIP', 'MIA2', 'MIPOL1', 'NFKBIA', 'NKX2-1', 'NKX2-1-AS1', 'NKX2-8', 'PAX9', 'PNN', 'PPP2R3C', 'PRORP', 'PSMA6', 'PTCSC3', 'RALGAPA1', 'SEC23A', 'SEC23A-AS1', 'SFTA3', 'SLC25A21', 'SLC25A21-AS1', 'SNORA101B', 'SSTR1', 'TRAPPC6B', 'TTC6']

Predicted Features

View Feature 1 - NCIH2170_LUNG BFB

Class	Amplicon	Complexity Score
BFB	1	1.286976489

View Feature 2 - NCIH2170_LUNG ecDNA

Class	Amplicon	Complexity Score
ecDNA	2	1.049548092

View Feature 3 - NCIH2170_LUNG ecDNA

Class	Amplicon	Complexity Score
ecDNA	3	1.038279323

Prediction

ecDNA: None

Prediction

Shatterseek Prediction: High Confidence

Shatterseek High Confidence Chromosomes: 9

Shatterseek Low Confidence Chromosomes: None