NCIH209_LUNG


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction
  • Circle Hunter Prediction
  • Shatterseek Prediction

ID Value
ATCC HTB-172
DSMZ ACC-499
Cellosaurus NCI-H209
Cosmic 688013.0

Property Value
% Polyploidy 1.3
Ploidy Classification hyperdiploid
Modal Chromosome Number 49.0
Modal Range Numeric 47-57
Marker Chromosomes Average Field 11.0
Primary or Metastasis Metastasis
Count of SV's 6

Details

ecDNA Present (Y/N/P): N

Literature source: https://aacrjournals.org/cancerdiscovery/article/13/4/928/725029/Extrachromosomal-DNA-Amplification-Contributes-to

HSR Classification: Y

ATCC Karyotype: This is a hyperdiploid human cell line., The modal chromosome number is 49, occurring at 28% with a frequency of higher ploidies of 1.3%. Ten to eleven markers were common to all cells including: der(1)t(1;3)(p22;p21), del(6)(q21), t(8q18q), del(12)(q13), der(14)t(14;?)(q32;?)., All had a single copy per cell. About 6 other markers were found, but they occurred only once in all metaphases karyotyped. Neither HSR nor DM were detected., Structurally normal B group chromosomes were not detected. All C group chromosomes were paired. A single copy of both the X and Y was found in all cells.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: Neither HSR nor DM were detected

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: N

Predicted Amplicon Classes: ['Linear amplification']

Predicted Genes on ecDNA

[]

Predicted Features

Class Amplicon Complexity Score
Linear amplification 1 0.6828581225
Image 1

Prediction

ecDNA: negative


Prediction

Shatterseek Prediction: High Confidence

Shatterseek High Confidence Chromosomes: 6

Shatterseek Low Confidence Chromosomes: None