Property | Value |
---|---|
% Polyploidy | None |
Ploidy Classification | mix(hypotriploid, triploid) |
Modal Chromosome Number | 68.0 |
Modal Range Numeric | 66-71 |
Marker Chromosomes Average Field | 15.0 |
Primary or Metastasis | Metastasis |
Count of SV's | 6 |
ecDNA Present (Y/N/P): N
Literature source:
https://aacrjournals.org/cancerdiscovery/article/13/4/928/725029/Extrachromosomal-DNA-Amplification-Contributes-to
HSR Classification: Y
ATCC Karyotype: This is a near triploid human cell line. The modal chromosome number is 68, but cells with 66, 70 and 71 chromosomes also occurred frequently. At least 15 markers were common to all cells including single copies of der(1)t(1;13)(p32;q12) and del(3)(p21/22), and paired der(7)t(7;?)(p22;?), t(13q16q) and t(16p21q). Ten others were seen in single copies or paired. No HSR or DM were found. Structurally normal N5, N13 and N14 were absent. Four or more copies of N18 and N20 were present in each cell, and N5, N7 and N11 were mostly single copies per cell. The X chromosomes were paired, and no Y chromosome was detected in QM stained preparations.
DSMZ Karyotype: No data
Heterogeneity Indications and Other Notes: No HSR or DM were found
ecDNA Amplicon Predicted: Y
Predicted Amplicon Classes: ['Linear amplification', 'ecDNA']
View Feature 1 - NCIH146_LUNG Linear amplification
Class | Amplicon | Complexity Score |
---|---|---|
Linear amplification | 1 | 0.6073076124 |
View Feature 2 - NCIH146_LUNG ecDNA
Class | Amplicon | Complexity Score |
---|---|---|
ecDNA | 2 | 0.6869072775 |
View Feature 3 - NCIH146_LUNG Linear amplification
Class | Amplicon | Complexity Score |
---|---|---|
Linear amplification | 3 | 1.010240424 |
ecDNA: None
Shatterseek Prediction: Low Confidence
Shatterseek High Confidence Chromosomes: None
Shatterseek Low Confidence Chromosomes: 6, 11