MSTO211H_PLEURA


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Shatterseek Prediction

ID Value
ATCC CRL-2081
DSMZ ACC-390
Cellosaurus MSTO-211H
Cosmic 908152.0

Property Value
% Polyploidy None
Ploidy Classification hypertriploid
Modal Chromosome Number 79.0
Modal Range Numeric 77-80
Marker Chromosomes Average Field 1.0
Primary or Metastasis Metastasis
Count of SV's 11

Details

ecDNA Present (Y/N/P): Y

HSR Classification: N

ATCC Karyotype: modal number = 72; range = 70 to 78

DSMZ Karyotype: human hypertriploid karyotype - 79(77-80)<3n>XYY/XXYY, +2, +4, +7, +7, +7, -10, +12, +13, +14, -15, -15, +16, +16, +16, -17, +18, -22, +1-2mar, 1-20dmin - add(1)(p35-36), add(1)(p34), der(4)t(4;17)(p14;q21)x2, del(6)(q25)x2, del(7)(q11), del(7)(q21.2)x2, inv(9)(p24q34), del(10)(q24), add(14)(p11), add(15)(p11), i?dic(16)(q10)x2 - sideline with der(6;9)(p10;q10) - high 7p copy number associated with poor prognosis mesothelioma - resembles published karyotype

Heterogeneity Indications and Other Notes: 1-20dmin

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA', 'Complex non-cyclic']

Predicted Genes on ecDNA

['CASC11', 'MYC', 'PVT1', 'TMEM75']

Predicted Features

Class Amplicon Complexity Score
ecDNA 1 0.097531054
Image 1

Class Amplicon Complexity Score
Complex non-cyclic 3 0.9914253041
Image 2

Prediction

ecDNA: None


Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 9