Available Data

Vendor Karyotype
Amplicon Architect Prediction
Shatterseek Prediction

ID	Value
ATCC	None
DSMZ	ACC-409
Cellosaurus	None
Cosmic	925340.0

Karyotype Details

Property	Value
% Polyploidy	8.0
Ploidy Classification	hypertriploid
Modal Chromosome Number	None
Modal Range Numeric	70-73
Marker Chromosomes Average Field	20.0
Primary or Metastasis	Metastasis
Count of SV's	14

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human hypertriploid karyotype with 8% polyploidy - 70-73<3n>XX/XXX, -X, -2, -2, -4, -5, -5, +6, -11, -13, -13, -14, -18, -19, -20, -21, -22, +20mar, add(X)(q1?), der(1)(1pter->p21::1p11->q32::1q44->q11::?), i(2p), der(3)t(3;?9)(p14;q13/21), del(4)(q21), del(4)(q26), del(6)(q1?)x2, del(7)(p11), del(8)(p12), add(8)(q24), del(9)(p11), add(13)(p11), inv(16)(p13q22), add(17)(p1?), add(19)(q13), i(21q) - resembles published karyotype

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA', 'Complex non-cyclic', 'Linear amplification']

Predicted Genes on ecDNA

['ADAMTSL4', 'ADAMTSL4-AS1', 'ECM1', 'FALEC', 'MCL1', 'TARS2', 'AASS', 'ANKRD7', 'ASZ1', 'CADPS2', 'CAPZA2', 'CAV1', 'CAV2', 'CFTR', 'CFTR-AS1', 'CPED1', 'CTTNBP2', 'FAM3C', 'FEZF1', 'FEZF1-AS1', 'ING3', 'KCND2', 'LSM8', 'MET', 'PTPRZ1', 'ST7', 'ST7-AS1', 'ST7-AS2', 'ST7-OT3', 'ST7-OT4', 'TES', 'TSPAN12', 'WNT16', 'WNT2', 'BBOX1', 'BBOX1-AS1', 'BDNF', 'BDNF-AS', 'CCDC34', 'CCDC82', 'FIBIN', 'JRKL', 'JRKL-AS1', 'KIF18A', 'LGR4', 'LGR4-AS1', 'LIN7C', 'MAML2']

Predicted Features

View Feature 1 - MKN45_STOMACH ecDNA

Class	Amplicon	Complexity Score
ecDNA	1	0.6928126287

View Feature 2 - MKN45_STOMACH ecDNA

Class	Amplicon	Complexity Score
ecDNA	2	1.342053835

View Feature 3 - MKN45_STOMACH ecDNA

Class	Amplicon	Complexity Score
ecDNA	2	0.3977504983

View Feature 4 - MKN45_STOMACH ecDNA

Class	Amplicon	Complexity Score
ecDNA	3	1.036628121

View Feature 5 - MKN45_STOMACH Complex non-cyclic

Class	Amplicon	Complexity Score
Complex non-cyclic	4	0.9854267261

View Feature 6 - MKN45_STOMACH Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	5	0.874608145

View Feature 7 - MKN45_STOMACH Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	6	0.6172383634

Prediction

ecDNA: None

Prediction

Shatterseek Prediction: High Confidence

Shatterseek High Confidence Chromosomes: 8, 11

Shatterseek Low Confidence Chromosomes: 6, 10, 12, 14