MFE280_ENDOMETRIUM


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Shatterseek Prediction

ID Value
ATCC None
DSMZ ACC-410
Cellosaurus None
Cosmic 908129.0

Property Value
% Polyploidy 24.0
Ploidy Classification hyperdiploid
Modal Chromosome Number 52.0
Modal Range Numeric 48-52
Marker Chromosomes Average Field 18.0
Primary or Metastasis Primary
Count of SV's 5

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human hyperdiploid karyotype with 24% polyploidy - 52(48-52)<2n>X, -X, +1, +1, -2, +9, -10, -12, -13, -16, -17, -17, -18, -19, -20, -22, +18mar, add(1)(p34), add(1)(p3?), add(1)(q11), add(3)(q13), add(3)(q27-29), add(4)(p14), der(9)t(9;13)(p11;q11), add(15)(p11) - near diploidy and gain of 1q typical in endometrial carcinoma

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA', 'Linear amplification', 'Complex non-cyclic']

Predicted Genes on ecDNA

['CLDN11', 'GPR160', 'LRRC31', 'LRRC34', 'LRRIQ4', 'PHC3', 'PRKCI', 'SAMD7', 'SEC62', 'SKIL', 'SLC7A14', 'SLC7A14-AS1', 'ADK', 'COMTD1', 'DUPD1', 'DUSP13', 'KAT6B', 'SAMD8', 'SNORD172', 'VDAC2', 'ARCN1', 'DDX6', 'IFT46', 'KMT2A', 'PHLDB1', 'TMEM25', 'TREH', 'TTC36', 'ANAPC7', 'ARPC3', 'ATP2A2', 'FAM216A', 'GPN3', 'IFT81', 'PPTC7', 'RAD9B', 'VPS29', 'LAPTM5', 'MATN1', 'MATN1-AS1', 'NKAIN1', 'PUM1', 'SDC3', 'SNORD103A', 'SNORD103B', 'SNORD103C', 'SNRNP40', 'ZCCHC17', 'PPP1R1B', 'STARD3', 'COL18A1', 'SLC19A1', 'CGN', 'FXYD3', 'GBAT2', 'GRAMD1A', 'HPN', 'HPN-AS1', 'PI4KB', 'PIP5K1A', 'POGZ', 'PSMB4', 'PSMD4', 'RFX5', 'SCN1B', 'SELENBP1', 'TUFT1', 'ZNF30', 'ZNF30-AS1', 'ZNF687', 'ZNF687-AS1', 'ZNF792', 'CDK2', 'DGKA', 'ERBB3', 'ESYT1', 'IKZF4', 'LBH', 'MYL6', 'MYL6B', 'PA2G4', 'PMEL', 'PYM1', 'RAB5B', 'RNF41', 'RPL41', 'RPS26', 'SMARCC2', 'SNORA10B', 'SUOX', 'YPEL5', 'ZC3H10', 'ALS2CL', 'FAM240A', 'PRSS45P', 'PRSS46P', 'PRSS50', 'TMIE', 'CLRN1', 'CLRN1-AS1']

Predicted Features

Class Amplicon Complexity Score
ecDNA 10 0.6377390049
Image 1

Class Amplicon Complexity Score
Linear amplification 11 0.6211569761
Image 2

Class Amplicon Complexity Score
Complex non-cyclic 12 0.9744401431
Image 3

Class Amplicon Complexity Score
Linear amplification 13 0.3200646429
Image 4

Class Amplicon Complexity Score
Linear amplification 14 1.014022743
Image 5

Class Amplicon Complexity Score
ecDNA 15 1.00126512
Image 6

Class Amplicon Complexity Score
ecDNA 16 0.6412921077
Image 7

Class Amplicon Complexity Score
ecDNA 17 0.6924192701
Image 8

Class Amplicon Complexity Score
Linear amplification 18 0.6313897909
Image 9

Class Amplicon Complexity Score
Linear amplification 19 0.7228970883
Image 10

Class Amplicon Complexity Score
ecDNA 1 0.5804403076
Image 11

Class Amplicon Complexity Score
ecDNA 20 0.4150522003
Image 12

Class Amplicon Complexity Score
Linear amplification 21 0.6400219205
Image 13

Class Amplicon Complexity Score
ecDNA 22 0.6418477487
Image 14

Class Amplicon Complexity Score
Linear amplification 2 0.0
Image 15

Class Amplicon Complexity Score
ecDNA 3 0.6725833286
Image 16

Class Amplicon Complexity Score
Linear amplification 4 0.9683582165
Image 17

Class Amplicon Complexity Score
ecDNA 5 0.6478912984
Image 18

Class Amplicon Complexity Score
ecDNA 6 0.5043533245
Image 19

Class Amplicon Complexity Score
Linear amplification 7 0.6559360988
Image 20

Class Amplicon Complexity Score
ecDNA 8 0.5832201761
Image 21

Class Amplicon Complexity Score
ecDNA 9 0.6352573662
Image 22

Prediction

ecDNA: None


Prediction

Shatterseek Prediction: High Confidence

Shatterseek High Confidence Chromosomes: 13

Shatterseek Low Confidence Chromosomes: 3