MDAMB361_BREAST


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Shatterseek Prediction

ID Value
ATCC HTB-27
DSMZ None
Cellosaurus MDA-MB-361
Cosmic 908121.0

Property Value
% Polyploidy None
Ploidy Classification hyperdiploid
Modal Chromosome Number 56.0
Modal Range Numeric 54-61
Marker Chromosomes Average Field 18.0
Primary or Metastasis Metastasis
Count of SV's 0

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: modal number. = 56; range = 54 to 61.The cell line is aneuploid human female, with chromosome counts in the hyperdiploid range. Normal chromosomes N11 and N17 are absent, chromosomes N1, N20, and N21 are weakly represented, and chromosomes N2, N8, N9, and N15 are single. The remainder of chromosomes are often paired. Eighteen marker chromosomes are found, of which 10 are consistently present. Some of these markers are found to be quite comparable to those described by K.L. Satya-Prakash, et al., in their report on this cell line.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Linear amplification', 'ecDNA', 'Complex non-cyclic']

Predicted Genes on ecDNA

['ANO1', 'CCND1', 'CTTN', 'FADD', 'FGF19', 'FGF3', 'FGF4', 'LTO1', 'MRGPRD', 'MRGPRF', 'MRGPRF-AS1', 'MYEOV', 'PPFIA1', 'SMIM38', 'TPCN2']

Predicted Features

Class Amplicon Complexity Score
Linear amplification 1 0.0
Image 1

Class Amplicon Complexity Score
ecDNA 2 0.6921100877
Image 2

Class Amplicon Complexity Score
Complex non-cyclic 3 1.598131751
Image 3

Class Amplicon Complexity Score
Complex non-cyclic 4 2.286530849
Image 4

Prediction

ecDNA: None


Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 1, 3, 6, 7, 12, 16