MDAMB157_BREAST


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Circle Hunter Prediction

ID Value
ATCC HTB-24
DSMZ None
Cellosaurus MDA-MB-157
Cosmic 925338.0

Property Value
% Polyploidy None
Ploidy Classification hyperdiploid
Modal Chromosome Number None
Modal Range Numeric 52-54
Marker Chromosomes Average Field 17.0
Primary or Metastasis Metastasis
Count of SV's 8

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: modal number =52 to 54; range = 52 to 69. Most of the karyotypes had three normal X chromosomes. Normal chromosomes N1, N5, N13, N14, N15, N16, N19, and N22 were not found. Seventeen marker chromosomes were identified: t(10q14q) der(12)t(1;12)(q21;p13), der(7)t(7;?)(q22;?), del(1)(q11), t(3qter>3q21::10p15>10qter), 7q+, del(5)(q13), 19q+, t(10q;14q), der(4)t(1;4)(q21;q25), 9q+, 13p+, 15p+ unknown, unknown, unknown, del(6)(q21). Marker chromosome M1 is similar to that described by Q.V. Cruciger, et al., Cytogenet. Cell Genet. 17: 231, 1976.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

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Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Linear amplification', 'ecDNA']

Predicted Genes on ecDNA

['METRNL', 'MIMT1', 'PEG3', 'PEG3-AS1', 'SMIM17', 'ZFP28', 'ZIM2', 'ZIM2-AS1', 'ZNF470', 'ZNF471', 'ZNF542P', 'ZNF582', 'ZNF582-AS1', 'ZNF583', 'ZNF667', 'ZNF667-AS1', 'ZNF71', 'ZNF71-SMIM17', 'ZNF835']

Predicted Features

Class Amplicon Complexity Score
Linear amplification 1 0.7592791322
Image 1

Class Amplicon Complexity Score
ecDNA 2 0.6252838626
Image 2

Class Amplicon Complexity Score
Linear amplification 3 0.6421259679
Image 3

Class Amplicon Complexity Score
ecDNA 4 0.7598145086
Image 4

Prediction

ecDNA: positive

Genes: .


Prediction

No data