MCF7_BREAST


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Circle Hunter Prediction

ID Value
ATCC CRL-12584
DSMZ ACC-115
Cellosaurus MCF-7
Cosmic 905946.0

Property Value
% Polyploidy 8.0
Ploidy Classification hypotetraploid
Modal Chromosome Number 86.0
Modal Range Numeric 80-87
Marker Chromosomes Average Field 7.0
Primary or Metastasis Metastasis
Count of SV's 10

Details

ecDNA Present (Y/N/P): N

HSR Classification: Y

ATCC Karyotype: No data

DSMZ Karyotype: human hypotetraploid karyotype with 8% polyploidy - 86(80-87)<4n>XX, -X, -X, -1, -1, +6, +7, -9, -10, -10, -12, -13, -13, +14, -17, -17, -18, -18, -20, -20, -20, -22, +6-8mar, add(X)(q27), add(2)(q35-37)x1-2, add(5)(p15), del(6)(q25)x1-2, add(7)(p11), add(7)(p14;hsr), add(10)(q23), del(11)(q21q23), add(15)(p11), i(15q), add(16)(q24), add(19)(q13), add(19)(p13)x1-2 - corresponds to published karyotype

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA', 'Linear amplification']

Predicted Genes on ecDNA

['APPBP2', 'ARFGEF2', 'ATXN7', 'BCAS1', 'BCAS3', 'BCAS4', 'BMP7', 'BMP7-AS1', 'BRIP1', 'C17orf64', 'C17orf82', 'C3orf14', 'C3orf49', 'CA4', 'CADPS', 'CLTC', 'CYP24A1', 'DHX40', 'EYA2', 'FEZF2', 'GDPD1', 'HEATR6', 'INTS2', 'MED13', 'NACA2', 'NCOA3', 'NTNG1', 'PARD6B', 'PPM1D', 'PPM1E', 'PREX1', 'PRICKLE2', 'PRICKLE2-AS1', 'PRICKLE2-AS2', 'PRMT6', 'PRR11', 'PSMD6', 'PSMD6-AS2', 'PTPRG', 'PTPRG-AS1', 'PTRH2', 'RAD51C', 'RNFT1', 'RNFT1-DT', 'RPS6KB1', 'RTEL1', 'RTEL1-TNFRSF6B', 'SCAANT1', 'SCARNA20', 'SKA2', 'SMG8', 'SNTN', 'SULF2', 'SUMO1P1', 'SYNPR', 'SYNPR-AS1', 'TANC2', 'TBC1D3P1-DHX40P1', 'TBX2', 'TBX2-AS1', 'TBX4', 'TEX14', 'THOC7', 'THOC7-AS1', 'TRIM37', 'TUBD1', 'USP32', 'VMP1', 'WFDC21P', 'YPEL2', 'ZMYND8', 'ZNF217', 'PLCG1', 'PLCG1-AS1', 'TOP1', 'DSCR4', 'DSCR8']

Predicted Features

Class Amplicon Complexity Score
ecDNA 1 1.408526829
Image 1

Class Amplicon Complexity Score
Linear amplification 2 0.0924989742
Image 2

Class Amplicon Complexity Score
Linear amplification 3 0.3527051107
Image 3

Class Amplicon Complexity Score
Linear amplification 4 0.3649066727
Image 4

Class Amplicon Complexity Score
Linear amplification 5 0.6857753906
Image 5

Class Amplicon Complexity Score
ecDNA 6 0.5494247407
Image 6

Class Amplicon Complexity Score
ecDNA 7 0.5430778805
Image 7

Prediction

ecDNA: positive

Genes: LOC1249243;RNU6-45P,NDUFB8P2;.;HMGB2P1;RPL5P3,RNU6-1157P


Prediction

No data