Available Data

Vendor Karyotype
Amplicon Architect Prediction
Circle Hunter Prediction
Shatterseek Prediction

ID	Value
ATCC	None
DSMZ	ACC-363
Cellosaurus	None
Cosmic	753576.0

Karyotype Details

Property	Value
% Polyploidy	8.0
Ploidy Classification	hypotriploid
Modal Chromosome Number	60.0
Modal Range Numeric	54-63
Marker Chromosomes Average Field	10.0
Primary or Metastasis	Primary
Count of SV's	14

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human hypotriploid karyotype with 8% polyploidy - 60(54-63)<3n>XXX, -Y, -2, -3, -3, -4, -6, +7, -8, -9, -10, -13, -14, -15, -16, -16, -16, -17, -18, -18, -21, -22, +10mar, del(X)(q25), add(1)(p11), add(2)(q33), del(2)(q33), del(3)(q13), add(4)(q35), add(5)(p15), del(5)(q14), add(7)(q36), del(7)(p11), del(8)(p22.2), qdp(9)(p11p24), add(10)(q25), add(11)(p?13), add(19)(p13), i(?22p)

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Complex non-cyclic', 'BFB', 'ecDNA', 'Linear amplification']

Predicted Genes on ecDNA

['ERMP1', 'GLDC', 'IL33', 'KDM4C', 'KIAA2026', 'MLANA', 'RANBP6', 'RIC1', 'TPD52L3', 'UHRF2', 'ABI1', 'ACBD5', 'ANKRD26', 'APBB1IP', 'ARMC4', 'ARMC4P1', 'BAMBI', 'C10orf126', 'ENKUR', 'FAM238A', 'FAM238B', 'FAM238C', 'GAD2', 'GPR158', 'GPR158-AS1', 'LRRC37A6P', 'LYZL1', 'MASTL', 'MKX', 'MKX-AS1', 'MPP7', 'MYO3A', 'PDSS1', 'PTCHD3', 'RAB18', 'SNORD130', 'SVIL', 'SVIL-AS1', 'WAC', 'WAC-AS1', 'YME1L1']

Predicted Features

View Feature 1 - KYSE70_OESOPHAGUS Complex non-cyclic

Class	Amplicon	Complexity Score
Complex non-cyclic	1	0.5163953231

View Feature 2 - KYSE70_OESOPHAGUS BFB

Class	Amplicon	Complexity Score
BFB	2	1.274032159

View Feature 3 - KYSE70_OESOPHAGUS ecDNA

Class	Amplicon	Complexity Score
ecDNA	3	0.6930670319

View Feature 4 - KYSE70_OESOPHAGUS ecDNA

Class	Amplicon	Complexity Score
ecDNA	4	0.685235599

View Feature 5 - KYSE70_OESOPHAGUS ecDNA

Class	Amplicon	Complexity Score
ecDNA	5	0.7052158673

View Feature 6 - KYSE70_OESOPHAGUS Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	6	0.5457299599

View Feature 7 - KYSE70_OESOPHAGUS BFB

Class	Amplicon	Complexity Score
BFB	7	0.978038484

Prediction

ecDNA: negative

Prediction

Shatterseek Prediction: High Confidence

Shatterseek High Confidence Chromosomes: 2, 4

Shatterseek Low Confidence Chromosomes: 7, 8