Available Data

Vendor Karyotype
Amplicon Architect Prediction
Shatterseek Prediction

ID	Value
ATCC	None
DSMZ	ACC-371
Cellosaurus	None
Cosmic	753575.0

Karyotype Details

Property	Value
% Polyploidy	8.0
Ploidy Classification	hypotriploid
Modal Chromosome Number	None
Modal Range Numeric	58-60
Marker Chromosomes Average Field	7.0
Primary or Metastasis	Primary
Count of SV's	19

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human flat-moded hypotriploid karyotype with 8% polyploidy - 58-60<3n>XX, -X, +1, +1, -2, -2, -4, -5, -6, +7, -8, -10, -10, -11, -12, -12, -13, -14, -15, -16, -17, -18, +20, +20, -21, -21, -22, -2, +7-8mar, add(X)(p11), add(X)(q11), add(1)(q11), der(1)del(1)(q12)t(1;7)(p36;q21), der(1)del(1)(q12)t(1;5)(p36;q11), del(1)(q21), del(1)(p34), add(2)(q37), del(3)(q13), add(4)(p11), add(4)(p15), add(5)(q11)x1-2, add(6)(q1?), t(6;15)(p10;q10)x1-2, del(7)(q11)x1-2, add(7)(p22), add(9)(p23), der(11)add(11)(p15)t(11;12)(q24;q11), add(11)(p15), add(16)(q2?3), add(17)(q24), add(18)(p11), add(19)(p13)del(22)(q13)

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Complex non-cyclic', 'Linear amplification', 'ecDNA']

Predicted Genes on ecDNA

['CCT6A', 'COBL', 'DDC', 'DDC-AS1', 'EGFR', 'EGFR-AS1', 'ELDR', 'FIGNL1', 'FKBP9P1', 'GRB10', 'IKZF1', 'LANCL2', 'MRPS17', 'NIPSNAP2', 'POM121L12', 'PSPH', 'SEC61G', 'SEPTIN14', 'SPATA48', 'VOPP1', 'VSTM2A', 'VSTM2A-OT1', 'ZNF713', 'ZPBP', 'KLF12', 'KLF5']

Predicted Features

View Feature 1 - KYSE520_OESOPHAGUS Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	10	0.5174828538

View Feature 2 - KYSE520_OESOPHAGUS Complex non-cyclic

Class	Amplicon	Complexity Score
Complex non-cyclic	1	1.819789452

View Feature 3 - KYSE520_OESOPHAGUS ecDNA

Class	Amplicon	Complexity Score
ecDNA	2	0.6904487443

View Feature 4 - KYSE520_OESOPHAGUS ecDNA

Class	Amplicon	Complexity Score
ecDNA	3	1.251579835

View Feature 5 - KYSE520_OESOPHAGUS Complex non-cyclic

Class	Amplicon	Complexity Score
Complex non-cyclic	4	0.719029407

View Feature 6 - KYSE520_OESOPHAGUS Complex non-cyclic

Class	Amplicon	Complexity Score
Complex non-cyclic	5	0.7904747915

View Feature 7 - KYSE520_OESOPHAGUS ecDNA

Class	Amplicon	Complexity Score
ecDNA	6	0.6926062612

View Feature 8 - KYSE520_OESOPHAGUS Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	7	0.4613790585

View Feature 9 - KYSE520_OESOPHAGUS Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	8	0.6180394299

View Feature 10 - KYSE520_OESOPHAGUS Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	9	0.0

Prediction

ecDNA: None

Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 13, 16