Available Data

Vendor Karyotype
Amplicon Architect Prediction

ID	Value
ATCC	None
DSMZ	ACC-8
Cellosaurus	None
Cosmic	909976.0

Karyotype Details

Property	Value
% Polyploidy	3.5
Ploidy Classification	hypotriploid
Modal Chromosome Number	59.0
Modal Range Numeric	56-60
Marker Chromosomes Average Field	25.0
Primary or Metastasis	Metastasis
Count of SV's	16

Details

ecDNA Present (Y/N/P): N

HSR Classification: Y

ATCC Karyotype: No data

DSMZ Karyotype: human hypotriploid karyotype with 3.5% polyploidy - 59(56-60)<3n>der(X)der(Y), -X, -1, -1, -2, -2, -3, -4, -5, -5, -6, -8, -9, -9, -10, -10, -10, -11, -12, -13, -14, -15, -15, -16, -16, -18, -19, -20, -21, -22, +25mar - add(1)(q32), add(3)(q26), add(3)(q26), del(4)(q26q31), i(4q), add(5)(p11), add(6)(q14), add(7)(p14), add(7)(q34), del(7)(q31), add(8)(q24), del(8)(p12), del(11)(q23), i(13q), der(13)t(11;13)(p13;q13), add(14)(p12)x2, del(17)(p12), i(18q) - apparently typical HD karyotype with extraordinary level of rearrangements including several HSR-bearing markers with ectopic rDNA - resembles published karyotype

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Linear amplification', 'ecDNA']

Predicted Genes on ecDNA

['PAPOLG', 'PUS10', 'REL', 'CD274', 'PDCD1LG2', 'PLGRKT', 'RIC1', 'SRGN', 'GRID1', 'WAPL', 'ABRAXAS2', 'CHST15', 'CPXM2', 'CTBP2', 'EEF1AKMT2', 'FAM53B', 'FAM53B-AS1', 'GPR26', 'LHPP', 'NKX1-2', 'OAT', 'ZRANB1']

Predicted Features

View Feature 1 - KMH2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	1	1.7e-09

View Feature 2 - KMH2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE ecDNA

Class	Amplicon	Complexity Score
ecDNA	2	0.9248198807

View Feature 3 - KMH2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE ecDNA

Class	Amplicon	Complexity Score
ecDNA	3	1.012789178

View Feature 4 - KMH2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE ecDNA

Class	Amplicon	Complexity Score
ecDNA	4	0.6886058617

View Feature 5 - KMH2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE ecDNA

Class	Amplicon	Complexity Score
ecDNA	5	0.68910524

View Feature 6 - KMH2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE ecDNA

Class	Amplicon	Complexity Score
ecDNA	6	0.6312078158

View Feature 7 - KMH2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	7	0.9517692984

View Feature 8 - KMH2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	8	0.4738673178

View Feature 9 - KMH2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	9	0.9825349345

Prediction

ecDNA: None

Prediction

No data