K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction
  • Circle Hunter Prediction

ID Value
ATCC CCL-243
DSMZ ACC-10
Cellosaurus K-562
Cosmic 905940.0

Property Value
% Polyploidy None
Ploidy Classification mix (triploid, hypotriploid)
Modal Chromosome Number None
Modal Range Numeric 61-68
Marker Chromosomes Average Field 2.0
Primary or Metastasis Metastasis
Count of SV's 3

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: The stemline chromosome number is triploid with the 2S component occurring at 4.2%. Fifteen markers (M1 and M(15)) occurred in nearly all S metaphases. Spontaneous non-specific dicentrics occurred, but rarely. Unstable markers were also rarely seen. The X was disomic, and N9 was nullisomic.

DSMZ Karyotype: human hypotriploid karyotype with sharp mode - 61-68<3n>XX, -X, -3, +7, -13, -18, +3mar, del(9)(p11/13), der(14)t(14;?)(p11;?), der(17)t(17;?)(p11/13;?), der(?18)t(15;?18)(q21;?q12), del(X)(p22) - two markers appear from FISH to have arisen from Ph;

Heterogeneity Indications and Other Notes: No data

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Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Linear amplification', 'Complex non-cyclic', 'ecDNA']

Predicted Genes on ecDNA

['GPC5']

Predicted Features

Class Amplicon Complexity Score
Linear amplification 1 1e-10
Image 1

Class Amplicon Complexity Score
Complex non-cyclic 2 1.43881705
Image 2

Class Amplicon Complexity Score
ecDNA 3 0.8032564044
Image 3

Class Amplicon Complexity Score
ecDNA 3 0.4070958913
Image 4

Class Amplicon Complexity Score
Linear amplification 4 0.5221948286
Image 5

Prediction

ecDNA: negative


Prediction

No data