Available Data

Vendor Karyotype
Amplicon Architect Prediction
Circle Hunter Prediction
Shatterseek Prediction

ID	Value
ATCC	CRL-1472
DSMZ	ACC-397
Cellosaurus	HT-1376
Cosmic	907066.0

Karyotype Details

Property	Value
% Polyploidy	8.0
Ploidy Classification	pentaploid
Modal Chromosome Number	111.0
Modal Range Numeric	102-116
Marker Chromosomes Average Field	7.0
Primary or Metastasis	Primary
Count of SV's	17

Details

ecDNA Present (Y/N/P): N

HSR Classification: Y

ATCC Karyotype: modal chromosome number = 104 to 121

DSMZ Karyotype: human flat-moded pentaploid karyotype with 8% polyploidy - 111(102-116)<5n>XX/XXX, +3, +3, +5, +5, -6, +7, +8, +8, -12, -13, -13, -14, -14, -15, -15, -15, -15, -16, -17,-17, -19, -19, +20, -22, -22, -22, +6-8mar - del(2)(q25), add(3)(q27)x2, del(3)(p11p14), i(5q), add(5)(p15), del(5)(p13), add(5)(q1?3;hsr), del(6)(q25), add(7)(p22), del(7)(q11), add(8)(p23)x2, i(9q)x2, del(9)(p21), del(10)(q24), add(11)(p15), add(12)(p13)x1-2, del(12)(p11), der(13)t(13;?)(p11;?)t(?;1)(?;q11), add(17)(p1?), add(18)(p11) - sideline with i(5p) - 3p, 5p/q10, +7, 8p, 9p, 10q, 11p, 17p rearrangements associated with bladder TCC - matches published karyotypes

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Linear amplification', 'ecDNA']

Predicted Genes on ecDNA

['ATF7IP2', 'BCAR4', 'CASC15', 'CDKAL1', 'CIITA', 'CLEC16A', 'CPPED1', 'DEXI', 'E2F3', 'EMP2', 'GSPT1', 'HDGFL1', 'ID4', 'LITAF', 'MBOAT1', 'NBAT1', 'NPIPB2', 'NUBP1', 'PRL', 'PRM1', 'PRM2', 'PRM3', 'RMI2', 'RSL1D1', 'SHISA9', 'SNN', 'SNX29', 'SOCS1', 'SOX4', 'TEKT5', 'TNFRSF17', 'TNP2', 'TVP23A', 'TXNDC11', 'ZC3H7A']

Predicted Features

View Feature 1 - HT1376_URINARY_TRACT Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	1	0.9859774111

View Feature 2 - HT1376_URINARY_TRACT Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	2	0.6847170317

View Feature 3 - HT1376_URINARY_TRACT ecDNA

Class	Amplicon	Complexity Score
ecDNA	3	0.6901838086

View Feature 4 - HT1376_URINARY_TRACT ecDNA

Class	Amplicon	Complexity Score
ecDNA	3	0.6801784313

View Feature 5 - HT1376_URINARY_TRACT Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	4	0.6790306217

View Feature 6 - HT1376_URINARY_TRACT Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	5	1.341098656

Prediction

ecDNA: negative

Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 5, 11