HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction

ID Value
ATCC CCL-240
DSMZ ACC-3
Cellosaurus HL-60
Cosmic 905938.0

Property Value
% Polyploidy 1.5
Ploidy Classification mix (diploid, hypotetraploid, hypodiploid)
Modal Chromosome Number None
Modal Range Numeric 82-88
Marker Chromosomes Average Field 3.0
Primary or Metastasis Primary
Count of SV's 9

Details

ecDNA Present (Y/N/P): Y

Literature source: https://www.nature.com/articles/nature21356

HSR Classification: Y

ATCC Karyotype: The stemline chromosome number is pseudodiploid with the 2S component occurring at 6.2%. Five markers (M2 through M6) were common to most S metaphases. DM's, which varied in numbers per cell, occurred in all metaphases karyotyped. HSR chromosomes were not detected.

DSMZ Karyotype: human flat-moded hypotetraploid karyotype with hypodiploid sideline and 1.5% polyploidy - 82-88<4n>XX, -X, -X, -8, -8, -16, -17, -17, +18, +22, +2mar, ins(1;8)(p?31;q24hsr)x2, der(5)t(5;17)(q11;q11)x2, add(6)(q27)x2, der(9)del(9)(p13)t(9;14)(q?22;q?22)x2, der(14)t(9;14)(q?22;q?22)x2, der(16)t(16;17)(q22;q22)x1-2, add(18)(q21) - sideline with: -2, -5, -15, del(11)(q23.1q23.2) - c-myc amplicons present in der(1) and in both markers

Heterogeneity Indications and Other Notes: c-myc amplicons present in der(1) and in both markers c-myc amplicons present in der(1) and in both markers

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Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA']

Predicted Genes on ecDNA

['CASC11', 'MYC']

Predicted Features

Class Amplicon Complexity Score
ecDNA 1 1.452152366
Image 1

Prediction

ecDNA: None


Prediction

No data