Available Data

Vendor Karyotype
Amplicon Architect Prediction
Shatterseek Prediction

ID	Value
ATCC	None
DSMZ	ACC-534
Cellosaurus	None
Cosmic	1240145.0

Karyotype Details

Property	Value
% Polyploidy	8.0
Ploidy Classification	hyperpentaploid
Modal Chromosome Number	None
Modal Range Numeric	120-124
Marker Chromosomes Average Field	10.0
Primary or Metastasis	Primary
Count of SV's	21

Details

ecDNA Present (Y/N/P): Y

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human flat-moded hyperpentaploid karyotype with 8% polyploidy - 120-124<5n>XX, +1, +1, +3, +3, -4, -4, -5, +7, +7, +7, -9, -9, -10, +11, -18, -21, -21, +22, +22, +22, +7-14mar, der(1)t(X;1)(q11;p11)x2, del(1)(q21)x2, i(1q), t(1;3)(p11;q11), add(2)(q?11), del(2)(p11), add(3)(q28), add(3)(p11), i(5p), add(8)(p2?), add(8)(q2?), add(8)(q24), der(9;19)(q10;q10)x2, add(10)(q2?5), add(11)(p13), der(11)add(11)(p1?1)add(11)(q25), add(12)(p13), add(16)(p11), add(17)(p1?2), add(18)(p11), del(20)(q12)x1-2, add(20)(q13)x2 - 2-6 dmin present in 80% cells

Heterogeneity Indications and Other Notes: 2-6 dmin present in 80% cells

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Complex non-cyclic', 'Linear amplification', 'ecDNA']

Predicted Genes on ecDNA

['CASC11', 'CASC19', 'CASC21', 'CASC8', 'CCAT1', 'CCAT2', 'MYC', 'PCAT2', 'POU5F1B', 'PRNCR1', 'PVT1', 'TMEM75']

Predicted Features

View Feature 1 - HCC44_LUNG Complex non-cyclic

Class	Amplicon	Complexity Score
Complex non-cyclic	1	1.532162645

View Feature 2 - HCC44_LUNG Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	2	1.214257775

View Feature 3 - HCC44_LUNG ecDNA

Class	Amplicon	Complexity Score
ecDNA	3	0.7567554408

Prediction

ecDNA: None

Prediction

Shatterseek Prediction: No Chromothripsis Detected

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: None