HCC33_LUNG


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction

ID Value
ATCC None
DSMZ ACC-487
Cellosaurus None
Cosmic 1303901.0

Property Value
% Polyploidy 8.0
Ploidy Classification hypotriploid
Modal Chromosome Number None
Modal Range Numeric 61-68
Marker Chromosomes Average Field 4.0
Primary or Metastasis Metastasis
Count of SV's 13

Details

ecDNA Present (Y/N/P): Y

Literature source: https://aacrjournals.org/cancerdiscovery/article/13/4/928/725029/Extrachromosomal-DNA-Amplification-Contributes-to

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human flat-moded hypotriploid karyotype with 8% polyploidy - 61-68<3n>XX, -Y, +1, +1, +3, -10, -12, -13, +17, -20, -22, +3-5 mar, ider(1)(q10)del(1)(?q12?q43)x2, add(1)(p36), del(1)(p32)x1-2, dup(2)(p23p24), der(3;17)(q10;q10)x1-2, add(8)(p11), del(9)(q21), der(12)t(11;12)(q13.4;q24.3), add(13)p11) - sideline with add(5)(p11), add(15)(p11), add(17)(p1?), del(22)(q12) - variable dmin present in most cells - dup(2) includes MYCN locus

Heterogeneity Indications and Other Notes: variable dmin present in most cells dup(2) includes MYCN locus

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA']

Predicted Genes on ecDNA

['CAP1', 'COL9A2', 'DDX51', 'EP400', 'EP400P1', 'GALNT9', 'MFSD2A', 'MYCL', 'NOC4L', 'PPT1', 'RLF', 'SNORA49', 'TMCO2', 'TRIT1', 'ZMPSTE24']

Predicted Features

Class Amplicon Complexity Score
ecDNA 1 0.7535540111
Image 1

Prediction

ecDNA: None


Prediction

No data