HCC1937_BREAST


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction

ID Value
ATCC CRL-2336
DSMZ ACC-513
Cellosaurus HCC1937
Cosmic 749714.0

Property Value
% Polyploidy None
Ploidy Classification hypertetraploid
Modal Chromosome Number 100.0
Modal Range Numeric 93-103
Marker Chromosomes Average Field 43.0
Primary or Metastasis Primary
Count of SV's 2

Details

ecDNA Present (Y/N/P): Y

Literature source: https://onlinelibrary.wiley.com/doi/epdf/10.1002/%28SICI%291097-0215%2819981209%2978%3A6%3C766%3A%3AAID-IJC15%3E3.0.CO%3B2-L

HSR Classification: N

ATCC Karyotype: CRL-2336 is highly transformed which is evident from the chromosome count and karyotype description. The modal chromosome number is 100. At least forty-three marker chromosomes, involving nearly every chromosome, were found. Chromosome 1 and chromosome 3 derivative chromosomes were verified using commercial whole chromosome paint (fluorescent in-situ hybridization (FISH)) probes. An acrocentric chromosome with an extra C-band at qter was detected (2 copies per metaphase). There were no normal X chromosomes however at least one derivative X was seen in each cell. The absence of a Y chromosome was verified by QM staining and C-bands. Normal copies of N1, N4, N15, N16 and N18 were absent.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: N

Predicted Amplicon Classes: ['BFB', 'Linear amplification']

Predicted Genes on ecDNA

[]

Predicted Features

Class Amplicon Complexity Score
BFB 1 0.7581143935
Image 1

Class Amplicon Complexity Score
Linear amplification 2 1.172842196
Image 2

Class Amplicon Complexity Score
Linear amplification 3 0.0
Image 3

Prediction

ecDNA: None


Prediction

No data