DU4475_BREAST


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction
  • Circle Hunter Prediction
  • Shatterseek Prediction

ID Value
ATCC CRL-7921
DSMZ ACC-427
Cellosaurus DU4475
Cosmic 906844.0

Property Value
% Polyploidy 12.0
Ploidy Classification tetraploid
Modal Chromosome Number None
Modal Range Numeric 88-93
Marker Chromosomes Average Field 4.0
Primary or Metastasis Metastasis
Count of SV's 11

Details

ecDNA Present (Y/N/P): N

Literature source: https://onlinelibrary.wiley.com/doi/full/10.1002/1098-2264%28200007%2928%3A3%3C308%3A%3AAID-GCC9%3E3.0.CO%3B2-B

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human flat-moded near-tetraploid karyotype with 12% polyploidy - 88-93<4n>XXXX, +1, +1, -5, -6, +9, -10, -10, +15, +15, -16, -16, +22, +4mar, i(1q)x2, ?add(1)(p35-36)x2, ?i(5p)x2, add(6)(p11), add(6)(p1?), del(6)(q25), add(9)(q35), del(11)(q24)x2, add(15)(p11)x2, add(17)(p1?)x2, del(21)(q22.2)x2 - sideline with -20, -20, +del(7)(p11) - gain of 1q and loss of 6q typical in breast carcinoma - resembles published karyotype

Heterogeneity Indications and Other Notes: No data

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Prediction

ecDNA Amplicon Predicted: N

Predicted Amplicon Classes: ['Linear amplification']

Predicted Genes on ecDNA

[]

Predicted Features

Class Amplicon Complexity Score
Linear amplification 1 1.011783442
Image 1

Prediction

ecDNA: negative


Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 2, 6, 15