Property | Value |
---|---|
% Polyploidy | 12.0 |
Ploidy Classification | hypotriploid |
Modal Chromosome Number | 62.0 |
Modal Range Numeric | 58-65 |
Marker Chromosomes Average Field | 3.0 |
Primary or Metastasis | Metastasis |
Count of SV's | 10 |
ecDNA Present (Y/N/P): N
Literature source:
https://www.nature.com/articles/nature21356
https://www.nature.com/articles/s41588-020-0678-2
HSR Classification: N
ATCC Karyotype: This is a hypotriploid human cell line. Both 61 and 62 chromosome numbers had the highest rate of occurrence in 30 metaphase counts.The rate of higher ploidies was 3%. The t(11q12q), del(11)(q23), 16q+, del(9)(p11), del(1)(p32) and 6 other marker chromosomes were found in most cells. The N13 was usually absent. The Y chromosome is abnormal through translocation to an unidentified chromosomal segment. The X chromosome was present in single copy.
DSMZ Karyotype: human hypotriploid karyotype with 12% polyploidy - 62(58-65)<3n>X, -X/Y, -X/Y, -2, -3, +5, -8, -10, -13, +15, +15, -16, -18, -19, -20, -21, -22, +3mar, del(1)(p31), del(2)(p11), i(5p), del(6)(q22), del(9)(p12), del(11)(q23), der(12)t(11;12)(q11;p11), add(13)(q33), add(13)(q33), add(15)(p11)x2, add(16)(q24) - closely resembles reported karyotype
Heterogeneity Indications and Other Notes: No data
ecDNA Amplicon Predicted: N
Predicted Amplicon Classes: ['Linear amplification']
View Feature 1 - DU145_PROSTATE Linear amplification
Class | Amplicon | Complexity Score |
---|---|---|
Linear amplification | 1 | 8e-10 |
View Feature 2 - DU145_PROSTATE Linear amplification
Class | Amplicon | Complexity Score |
---|---|---|
Linear amplification | 2 | 0.9269685279 |
View Feature 3 - DU145_PROSTATE Linear amplification
Class | Amplicon | Complexity Score |
---|---|---|
Linear amplification | 3 | 0.683979261 |
View Feature 4 - DU145_PROSTATE Linear amplification
Class | Amplicon | Complexity Score |
---|---|---|
Linear amplification | 4 | 0.9897707843 |
ecDNA: negative
Shatterseek Prediction: High Confidence
Shatterseek High Confidence Chromosomes: 6
Shatterseek Low Confidence Chromosomes: None