Available Data

Vendor Karyotype
Amplicon Architect Prediction

ID	Value
ATCC	CCL-224
DSMZ	None
Cellosaurus	COLO 201
Cosmic	None

Karyotype Details

Property	Value
% Polyploidy	None
Ploidy Classification	hypertriploid
Modal Chromosome Number	None
Modal Range Numeric	70-80
Marker Chromosomes Average Field	None
Primary or Metastasis	Metastasis
Count of SV's	0

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: The stemline chromosome number is hypertriploid and 10-11 marker chromosomes (M1, M2, M4, M5, M6 and 5 others) were common in monosomic, disomic and trisomic condition although most of these markers were monosomic.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA', 'Linear amplification', 'Complex non-cyclic']

Predicted Genes on ecDNA

['MUC20', 'SDHAP2', 'ADCY10P1', 'AHI1', 'ALDH8A1', 'APOBEC2', 'ATP6V0CP3', 'BICRAL', 'BTBD9', 'BTBD9-AS1', 'BYSL', 'C6orf132', 'C6orf226', 'CCND3', 'CT69', 'DAAM2', 'DAAM2-AS1', 'DNAH8', 'DNAH8-AS1', 'EYA4', 'FOXP4', 'FOXP4-AS1', 'FRS3', 'GLO1', 'GLP1R', 'GUCA1A', 'GUCA1B', 'HBS1L', 'HMGA1P7', 'KCNK16', 'KCNK17', 'KCNK5', 'KIF6', 'LRFN2', 'MDFI', 'MED20', 'MOCS1', 'MRPS10', 'MYB', 'NCR2', 'NFYA', 'OARD1', 'PGC', 'PRICKLE4', 'PRPH2', 'RPL7L1', 'SAYSD1', 'SGK1', 'SLC2A12', 'TAF8', 'TARID', 'TBCC', 'TBPL1', 'TCF21', 'TDRG1', 'TFEB', 'TOMM6', 'TREM1', 'TREM2', 'TREML1', 'TREML2', 'TREML3P', 'TREML4', 'TREML5P', 'TRERF1', 'TSPO2', 'UBR2', 'UNC5CL', 'USP49', 'ZFAND3', 'KLF14']

Predicted Features

View Feature 1 - COLO201_LARGE_INTESTINE ecDNA

Class	Amplicon	Complexity Score
ecDNA	1	0.6643668015

View Feature 2 - COLO201_LARGE_INTESTINE ecDNA

Class	Amplicon	Complexity Score
ecDNA	2	0.6860035378

View Feature 3 - COLO201_LARGE_INTESTINE Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	3	0.6088484139

View Feature 4 - COLO201_LARGE_INTESTINE ecDNA

Class	Amplicon	Complexity Score
ecDNA	4	0.6537741808

View Feature 5 - COLO201_LARGE_INTESTINE Complex non-cyclic

Class	Amplicon	Complexity Score
Complex non-cyclic	5	0.6786027884

View Feature 6 - COLO201_LARGE_INTESTINE Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	6	1.023068599

Prediction

ecDNA: None

Prediction

No data