CAMA1_BREAST


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction
  • Shatterseek Prediction

ID Value
ATCC HTB-21
DSMZ None
Cellosaurus CAMA-1
Cosmic 946382.0

Property Value
% Polyploidy 3.5
Ploidy Classification hypertriploid
Modal Chromosome Number 80.0
Modal Range Numeric 68-83
Marker Chromosomes Average Field None
Primary or Metastasis Metastasis
Count of SV's 4

Details

ecDNA Present (Y/N/P): Y

Literature source: https://onlinelibrary.wiley.com/doi/full/10.1002/1098-2264%28200007%2928%3A3%3C308%3A%3AAID-GCC9%3E3.0.CO%3B2-B

HSR Classification: N

ATCC Karyotype: modal number = 80; range = 68 to 83.This is a hypertriploid human cell line with the modal chromosome number of 80 occurring in 44% of a total of 88 cells examined. The rate of polyploid cells was 3.5%. Karyotypes of this cell line were generally uniform and stable. There were 12-13 marker chromosomes per cell, 11 of which were found in all cells, and 7 of which were mostly paired. Among the markers were paired mar(1qter--q21::?::6p11.2--6pter), t(3q::?), and i(16q); single der(12)t(12;?)(q24:?); and 8-9 others. Double minutes occurred in some cells; however, they were present as only one or two copies per cell. Structurally normal N16 was absent and N8 occurred in only a few cells. Paired normal X chromosomes were present in every cell.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: Double minutes occurred in some cells; however, they were present as only one or two copies per cell

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Complex non-cyclic', 'ecDNA']

Predicted Genes on ecDNA

['ADAM32', 'ADAM9', 'ADGRA2', 'ADRB3', 'ANO1', 'ARRB1', 'ASH2L', 'BAG4', 'BRF2', 'C8orf86', 'CCND1', 'CHRDL2', 'CPT1A', 'CTTN', 'DDHD2', 'EIF4EBP1', 'ERLIN2', 'FADD', 'FGF19', 'FGF3', 'FGF4', 'FGFR1', 'GAL', 'GDPD5', 'GOT1L1', 'HTRA4', 'IGHMBP2', 'KCNE3', 'KCNU1', 'KLHL35', 'LETM2', 'LIPT2', 'LSM1', 'LTO1', 'MAP6', 'MOGAT2', 'MRGPRD', 'MRGPRF', 'MRGPRF-AS1', 'MRPL21', 'MYEOV', 'NEU3', 'NSD3', 'OR2AT4', 'P4HA3-AS1', 'PGM2L1', 'PLEKHA2', 'PLPBP', 'PLPP5', 'POLD3', 'PPFIA1', 'RAB11FIP1', 'RNF169', 'RNF5P1', 'RPS3', 'SERPINH1', 'SLCO2B1', 'SMIM38', 'SNORD15A', 'SNORD15B', 'SNORD38D', 'SPCS2', 'STAR', 'TACC1', 'TESMIN', 'TM2D2', 'TPBGL', 'TPCN2', 'XRRA1', 'ZNF703']

Predicted Features

Class Amplicon Complexity Score
Complex non-cyclic 1 1.173038568
Image 1

Class Amplicon Complexity Score
ecDNA 2 0.5188049764
Image 2

Prediction

ecDNA: None


Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 1, 11