Available Data

Vendor Karyotype
Amplicon Architect Prediction
Shatterseek Prediction

ID	Value
ATCC	None
DSMZ	ACC-459
Cellosaurus	None
Cosmic	906826.0

Karyotype Details

Property	Value
% Polyploidy	20.0
Ploidy Classification	hypertetraploid
Modal Chromosome Number	98.0
Modal Range Numeric	88-98
Marker Chromosomes Average Field	17.0
Primary or Metastasis	Metastasis
Count of SV's	18

Details

ecDNA Present (Y/N/P): Y

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human hypertetraploid karyotype with 20% polyploidy 98(88-98)<4n>XXX/XXXX, -1, -2, -2, -4, +5, +5, +6, -9, -9, +10, +11, -12, -12, -13, -13, -14, -15, -16, -16, -20, -21, -22, +16-18mar, + 1-2 dmin, add(X)(p2?2), add(1)(q22), del(3)(q22), add(3)(p1?4), del(4)(p15.2), add(6)(q11)x2, del(7)(q32), add(8)(p12), add(8)(q24), der(8;13)(q10;q10), ins(11;?)(q13;?), add(12)(p1?), add(13)(p11)x1-2, add(14)(p11), der(15;?21)(p1?1;?q12)x3 - sideline with i(1)(p10)add(1)(p3?2), i(1q), i(3p), der(16)t(5;16)(q13;q24)

Heterogeneity Indications and Other Notes: 1-2 dmin

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA', 'Linear amplification', 'Complex non-cyclic']

Predicted Genes on ecDNA

['EXT1', 'SAMD12', 'SNORD168', 'ADGRA2', 'ADRB3', 'ASH2L', 'BAG4', 'BRF2', 'C8orf86', 'DDHD2', 'EIF4EBP1', 'ERLIN2', 'FGFR1', 'GOT1L1', 'KCNU1', 'LETM2', 'LSM1', 'NSD3', 'PLPBP', 'PLPP5', 'RAB11FIP1', 'RNF5P1', 'STAR', 'TACC1', 'ZNF703']

Predicted Features

View Feature 1 - CAL120_BREAST ecDNA

Class	Amplicon	Complexity Score
ecDNA	1	0.804986042

View Feature 2 - CAL120_BREAST Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	2	0.8678941947

View Feature 3 - CAL120_BREAST Complex non-cyclic

Class	Amplicon	Complexity Score
Complex non-cyclic	3	1.122404862

View Feature 4 - CAL120_BREAST Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	4	0.6656317258

View Feature 5 - CAL120_BREAST ecDNA

Class	Amplicon	Complexity Score
ecDNA	5	1.448984431

View Feature 6 - CAL120_BREAST Linear amplification

Class	Amplicon	Complexity Score
Linear amplification	6	1e-10

View Feature 7 - CAL120_BREAST Complex non-cyclic

Class	Amplicon	Complexity Score
Complex non-cyclic	7	2.328077376

Prediction

ecDNA: None

Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 10, 16