CAKI1_KIDNEY


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction
  • Circle Hunter Prediction
  • Shatterseek Prediction

ID Value
ATCC HTB-46
DSMZ ACC-142
Cellosaurus Caki-1
Cosmic 905963.0

Property Value
% Polyploidy None
Ploidy Classification hypotriploid
Modal Chromosome Number 68.0
Modal Range Numeric 63-71
Marker Chromosomes Average Field 13.0
Primary or Metastasis Metastasis
Count of SV's 5

Details

ecDNA Present (Y/N/P): Y

Literature source: https://www.nature.com/articles/nature21356

HSR Classification: N

ATCC Karyotype: modal number = 68; range = 63 to 71.The cell line is aneuploid human, with chromosome counts in the triploid range. The Y chromosome is absent; however, loss of the Y chromosome is not unusual from male tumor cell lines. All normal autosomes except chromosome N9 and N19 are represented, usually by two or three copies. Chromosome N9 is recognized as a marker chromosome (M1) that is usually trisomic. Normal chromosome N5 is and chromosomes N10 and N16 tend to be over-represented with respect to the copy number of other normal chromosomes. Thirteen marker chromosomes are identified: 9q+, t(1p;?), t(1qter>1q21::20), t(1q17q), der(11)t(3;11)(q21;q14), 19q+, 4q+, 4p+ and others. The chromosome counts and general cytogenetic features are in keeping with those described by J. Fogh, et al., J. Natl. Cancer Inst. (Bethesda) 58: 209, 1977.

DSMZ Karyotype: No data

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA']

Predicted Genes on ecDNA

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Predicted Features

Class Amplicon Complexity Score
ecDNA 1 0.8049447074
Image 1

Prediction

ecDNA: negative


Prediction

Shatterseek Prediction: Low Confidence

Shatterseek High Confidence Chromosomes: None

Shatterseek Low Confidence Chromosomes: 3