BT474_BREAST


Available Data

  • Vendor Karyotype
  • ecDNA Presence Verification from Literature
  • Amplicon Architect Prediction

ID Value
ATCC CRL-7913
DSMZ ACC-64
Cellosaurus BT-474
Cosmic 946359.0

Property Value
% Polyploidy None
Ploidy Classification mix(hypertetraploid, hypopentaploid)
Modal Chromosome Number 104.0
Modal Range Numeric 91-111
Marker Chromosomes Average Field None
Primary or Metastasis Primary
Count of SV's 0

Details

ecDNA Present (Y/N/P): N

Literature source: https://onlinelibrary.wiley.com/doi/full/10.1002/1098-2264%28200007%2928%3A3%3C308%3A%3AAID-GCC9%3E3.0.CO%3B2-B
https://www.nature.com/articles/nature21356

HSR Classification: N

ATCC Karyotype: No data

DSMZ Karyotype: human hypertetraploid karyotype - 104(91-111)<4n>

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['Complex non-cyclic', 'ecDNA', 'Linear amplification']

Predicted Genes on ecDNA

['ABCC3', 'ACACA', 'ACSF2', 'AMZ2P1', 'ANKRD40', 'ANKRD40CL', 'ARL5C', 'C17orf78', 'CACNA1G', 'CACNA1G-AS1', 'CACNB1', 'CDK12', 'CHAD', 'COL1A1', 'CSF3', 'DDX52', 'DLX3', 'DLX4', 'DUSP14', 'EME1', 'EPN3', 'ERBB2', 'FAM117A', 'FLJ45513', 'GRB7', 'GSDMA', 'GSDMB', 'H1-9P', 'HOXB-AS1', 'HOXB-AS3', 'HOXB1', 'HOXB13', 'HOXB2', 'HOXB3', 'HOXB4', 'HOXB5', 'HOXB6', 'HOXB7', 'HOXB8', 'HOXB9', 'IKZF3', 'ITGA3', 'KAT7', 'LRRC3C', 'LRRC59', 'LUC7L3', 'MED24', 'MIEN1', 'MRPL27', 'MYCBPAP', 'NEUROD2', 'ORMDL3', 'PDK2', 'PGAP3', 'PICART1', 'PLXDC1', 'PNMT', 'PPP1R1B', 'PPP1R9B', 'PRAC1', 'PRAC2', 'PSMD3', 'RPL19', 'RSAD1', 'SAMD14', 'SGCA', 'SKAP1', 'SNORA90', 'SNORD124', 'SPATA20', 'STAC2', 'STARD3', 'SYNRG', 'TAC4', 'TADA2A', 'TCAP', 'THRA', 'THRA1/BTR', 'TMEM92', 'TMEM92-AS1', 'TOB1', 'TTLL6', 'WFIKKN2', 'XYLT2', 'ZPBP2', 'APPBP2', 'BCAS3', 'C17orf64', 'CLTC', 'COX11', 'DHX40', 'GDPD1', 'HEATR6', 'HLF', 'MMD', 'PCTP', 'PPM1D', 'PRR11', 'PTRH2', 'RNFT1', 'RNFT1-DT', 'RPS6KB1', 'SMG8', 'STXBP4', 'TBC1D3P1-DHX40P1', 'TMEM100', 'TOM1L1', 'TUBD1', 'USP32', 'VMP1', 'YPEL2', 'TSPOAP1', 'TSPOAP1-AS1', 'ARID3C', 'ATP8B5P', 'C9orf131', 'CCL19', 'CCL21', 'CCL27', 'CNTFR', 'CNTFR-AS1', 'DCTN3', 'DNAI1', 'DNAJB5', 'DNAJB5-DT', 'ENHO', 'FAM205A', 'FAM205BP', 'FAM205C', 'FAM214B', 'FAM219A', 'FANCG', 'GALT', 'IL11RA', 'PHF24', 'PIGO', 'RPP25L', 'SIGMAR1', 'STOML2', 'UNC13B', 'VCP', 'ACSS2', 'ADA', 'ADNP', 'ADNP-AS1', 'ANKRD60', 'APCDD1L', 'APCDD1L-DT', 'ARFGEF2', 'ATP9A', 'AURKA', 'B4GALT5', 'BCAS1', 'BCAS4', 'BMP7', 'BMP7-AS1', 'C20orf173', 'C20orf85', 'CASS4', 'CBLN4', 'CCN5', 'CEBPB', 'CEBPB-AS1', 'CEP250', 'CSE1L', 'CSE1L-AS1', 'CSTF1', 'CTCFL', 'CYP24A1', 'DDX27', 'DOK5', 'DPM1', 'DYNLRB1', 'EDEM2', 'EIF6', 'FAM209A', 'FAM209B', 'FAM210B', 'FAM83C', 'FAM83C-AS1', 'GCNT7', 'GDF5', 'GDF5OS', 'GGT7', 'GNAS-AS1', 'GSS', 'HMGB3P1', 'HNF4A', 'ITCH', 'KCNB1', 'KCNG1', 'KCNK15', 'KCNK15-AS1', 'KCNS1', 'MAP1LC3A', 'MC3R', 'MMP24', 'MMP24-AS1-EDEM2', 'MMP24OS', 'MOCS3', 'MTRNR2L3', 'MYH7B', 'NCOA3', 'NCOA6', 'NFATC2', 'NKILA', 'NPEPL1', 'PABPC1L', 'PARD6B', 'PCK1', 'PFDN4', 'PHACTR3-AS1', 'PI3', 'PIGU', 'PKIG', 'PMEPA1', 'PPP4R1L', 'PREX1', 'PROCR', 'PTGIS', 'PTPN1', 'RAB22A', 'RAE1', 'RBM38', 'RIMS4', 'RIPOR3', 'RNF114', 'RTF2', 'SALL4', 'SEMG1', 'SEMG2', 'SERINC3', 'SLC9A8', 'SMIM25', 'SNAI1', 'SNORD12', 'SNORD12B', 'SNORD12C', 'SPATA2', 'SPO11', 'STAU1', 'STK4', 'STK4-AS1', 'STX16', 'STX16-NPEPL1', 'SULF2', 'SUMO1P1', 'TFAP2C', 'TMEM189', 'TMEM189-UBE2V1', 'TOMM34', 'TP53INP2', 'TRERNA1', 'TRPC4AP', 'TSHZ2', 'TTPAL', 'UBE2V1', 'UQCC1', 'VAPB', 'WFDC12', 'WFDC5', 'YWHAB', 'ZBP1', 'ZFAS1', 'ZFP64', 'ZMYND8', 'ZNF217', 'ZNFX1', 'IPW', 'NPAP1', 'PWAR1', 'PWAR4', 'PWAR5', 'PWAR6', 'PWARSN', 'PWRN1', 'PWRN2', 'PWRN4', 'SNHG14', 'SNORD107', 'SNORD108', 'SNORD109A', 'SNORD109B', 'SNORD115-1', 'SNORD115-10', 'SNORD115-11', 'SNORD115-12', 'SNORD115-13', 'SNORD115-14', 'SNORD115-15', 'SNORD115-16', 'SNORD115-17', 'SNORD115-18', 'SNORD115-19', 'SNORD115-2', 'SNORD115-20', 'SNORD115-21', 'SNORD115-22', 'SNORD115-23', 'SNORD115-24', 'SNORD115-25', 'SNORD115-26', 'SNORD115-27', 'SNORD115-28', 'SNORD115-29', 'SNORD115-3', 'SNORD115-30', 'SNORD115-31', 'SNORD115-32', 'SNORD115-33', 'SNORD115-34', 'SNORD115-35', 'SNORD115-36', 'SNORD115-37', 'SNORD115-38', 'SNORD115-39', 'SNORD115-4', 'SNORD115-40', 'SNORD115-41', 'SNORD115-42', 'SNORD115-43', 'SNORD115-44', 'SNORD115-45', 'SNORD115-46', 'SNORD115-47', 'SNORD115-48', 'SNORD115-5', 'SNORD115-6', 'SNORD115-7', 'SNORD115-8', 'SNORD115-9', 'SNORD116-1', 'SNORD116-10', 'SNORD116-11', 'SNORD116-12', 'SNORD116-13', 'SNORD116-14', 'SNORD116-15', 'SNORD116-16', 'SNORD116-17', 'SNORD116-18', 'SNORD116-19', 'SNORD116-2', 'SNORD116-20', 'SNORD116-21', 'SNORD116-22', 'SNORD116-23', 'SNORD116-24', 'SNORD116-25', 'SNORD116-26', 'SNORD116-27', 'SNORD116-28', 'SNORD116-29', 'SNORD116-3', 'SNORD116-30', 'SNORD116-4', 'SNORD116-5', 'SNORD116-6', 'SNORD116-7', 'SNORD116-8', 'SNORD116-9', 'SNORD64', 'SNRPN', 'SNURF']

Predicted Features

Class Amplicon Complexity Score
Complex non-cyclic 1 1.490284279
Image 1

Class Amplicon Complexity Score
ecDNA 2 1.00535297
Image 2

Class Amplicon Complexity Score
ecDNA 2 0.8891756366
Image 3

Class Amplicon Complexity Score
ecDNA 2 0.6157779193
Image 4

Class Amplicon Complexity Score
ecDNA 2 1.614256695
Image 5

Class Amplicon Complexity Score
ecDNA 2 0.4463721276
Image 6

Class Amplicon Complexity Score
ecDNA 2 0.6262623982
Image 7

Class Amplicon Complexity Score
Complex non-cyclic 3 0.855343605
Image 8

Class Amplicon Complexity Score
Linear amplification 4 0.6961493385
Image 9

Class Amplicon Complexity Score
ecDNA 5 1.13721397
Image 10

Class Amplicon Complexity Score
Linear amplification 6 0.9410137086
Image 11

Class Amplicon Complexity Score
Complex non-cyclic 7 1.700888316
Image 12

Prediction

ecDNA: None


Prediction

No data