A431_SKIN


Available Data

  • Vendor Karyotype
  • Amplicon Architect Prediction

ID Value
ATCC CRL-1555
DSMZ ACC-91
Cellosaurus A-431
Cosmic 910925.0

Property Value
% Polyploidy 24.0
Ploidy Classification hypertriploid
Modal Chromosome Number 74.0
Modal Range Numeric 70-80
Marker Chromosomes Average Field 2.0
Primary or Metastasis Primary
Count of SV's 11

Details

ecDNA Present (Y/N/P): N

HSR Classification: N

ATCC Karyotype: This is a hypertriploid human cell line. The modal chromosome number was 74 occurring in 36% of cells. The rate of cells with higher ploidies was 1.0%.

DSMZ Karyotype: human hypotriploid karyotype with 24% polyploidy - 64(58-64)<3n>XX/XXX, -2, +3, +7, -8, +10, -11, -13, -14, -15, -16, -18, -22, +2mar - del(3)(p11)x1-2, add(4)(p15), add(6)(p21.3), del(7)(p15), der(7)t(7;11)(p11/13;q11/13)add(11)(q23), add(8)(p21), add(11)(q23), der(14)t(13;14)(q11;p11), add(16)(p13) - carries t(7;11) with breakpoint at EGFR (which it overexpresses) - corresponds to published karyotype

Heterogeneity Indications and Other Notes: No data

Download Breakpoint Edges CSV

Prediction

ecDNA Amplicon Predicted: Y

Predicted Amplicon Classes: ['ecDNA', 'BFB']

Predicted Genes on ecDNA

['EGFR', 'EGFR-AS1', 'ELDR', 'LANCL2', 'VOPP1', 'C14orf39', 'DHRS7', 'LRRC9', 'PCNX4', 'PPM1A']

Predicted Features

Class Amplicon Complexity Score
ecDNA 1 0.6903049816
Image 1

Class Amplicon Complexity Score
BFB 2 1.35981039
Image 2

Class Amplicon Complexity Score
ecDNA 3 0.6713904374
Image 3

Prediction

ecDNA: None


Prediction

No data